3-(p-fluorophenyl)-2-methyl-4(3h)-quinazolinon

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Names

[ CAS No. ]:
1897-80-9

[ Name ]:
3-(p-fluorophenyl)-2-methyl-4(3h)-quinazolinon

[Synonym ]:
B 228
3-<4-Fluor-phenyl>-2-methyl-3H-chinazolin-4-on

Chemical & Physical Properties

[ Density]:
1.25g/cm3

[ Boiling Point ]:
411.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₅H₁₁FN₂O

[ Molecular Weight ]:
254.25900

[ Flash Point ]:
202.6ºC

[ Exact Mass ]:
254.08600

[ PSA ]:
34.89000

[ LogP ]:
2.83320

[ Vapour Pressure ]:
5.62E-07mmHg at 25°C

[ Index of Refraction ]:
1.621

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA3408000

CHEMICAL NAME :: 4(3H)-Quinazolinone, 3-(p-fluorophenyl)-2-methyl-

CAS REGISTRY NUMBER :: 1897-80-9

BEILSTEIN REFERENCE NO. :: 0886566

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H11-F-N2-O

MOLECULAR WEIGHT :: 254.28

WISWESSER LINE NOTATION :: T66 BVN ENJ CR DF& E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,688,1963

Synthetic Route

Click to get detail synthetic route

Related Compounds

3-(p-chlorophenyl)-2-methyl-4(3h)-quinazolinon
3-(p-Ethoxyphenyl)-2-methyl-4(3H)-pteridinone
1-(4-bromophenyl)-3-(2-methyl-4-oxoquinazolin-3-yl)thiourea
6-bromo-3-[4-(6-bromo-2-methyl-4-oxoquinazolin-3-yl)phenyl]-2-methylquinazolin-4-one
1,3-Butanediol, 1-(p-fluorophenyl)-2-methyl-4,4,4-trifluoro-3-(trifluo romethyl)-, 3,4-dichlorocarbanilate
1-(4-chlorophenyl)-3-(2-methyl-4-oxoquinazolin-3-yl)thiourea