tert-butyl (3S,4S)-3-amino-4-hydroxypyrrolidine-1-carboxylate

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Names

[ CAS No. ]:
190792-74-6

[ Name ]:
tert-butyl (3S,4S)-3-amino-4-hydroxypyrrolidine-1-carboxylate

[Synonym ]:
(3S,4S)-tert-Butyl-3-amino-4-hydroxypyrrolidine-1-carboxylate
(3R,4R)-tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
(3R,4R)-tert-Butyl-3-amino-4-hydroxypyrrolidine-1-carboxylate
Trans-3-amino-1-BOC-4-hydroxypyrpolidine
H-STA-OH
STATIN
tert-Butyl (3S,4S)-3-amino-4-hydroxypyrrolidine-1-carboxylate
1-Pyrrolidinecarboxylic acid, 3-amino-4-hydroxy-, 1,1-dimethylethyl ester, (3S,4S)-
2-Methyl-2-propanyl (3S,4S)-3-amino-4-hydroxy-1-pyrrolidinecarboxylate
trans-3-amino-1-tert-butoxycarbonyl-4-hydroxypyrrolidine
LEU-STATINE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
308.8±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₈N₂O₃

[ Molecular Weight ]:
202.251

[ Flash Point ]:
140.5±27.9 °C

[ Exact Mass ]:
202.131744

[ PSA ]:
75.79000

[ LogP ]:
-0.81

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.518

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(3S,4S)-3-azido-4-(trimethylsilanyloxy)pyrrolidine-1-carboxylic acid tert-butyl ester
Di-tert-butyl dicarbonate
(3S,4S)-TERT-BUTYL 3-(BENZYLAMINO)-4-HYDROXYPYRROLIDINE-1-CARBOXYLATE
tert-Butyl carbamate
N-Boc-3-pyrroline
3-Boc-6-oxa-3-aza-bicyclo[3.1.0]hexane