4-Nitrophenyl 4-Guanidinobenzoate Hydrochloride

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Names

[ CAS No. ]:
19135-17-2

[ Name ]:
4-Nitrophenyl 4-Guanidinobenzoate Hydrochloride

[Synonym ]:
NPGB
4-Guanidinobenzoic acid 4-nitrophenylester hydrochloride NPGB pNPGB
(4-nitrophenyl) 4-(diaminomethylideneamino)benzoate hydrochloride
pNPGB
4-Nitrophenyl 4-guanidinobenzoate hydrochloride
4-Guanidinobenzoic acid 4-nitrophenylester hydrochloride
MFCD00037010
4-Nitrophenyl 4-Guanidinobenzoate Hydrochloride

Chemical & Physical Properties

[ Density]:
1.44g/cm3

[ Boiling Point ]:
559.7ºC at 760mmHg

[ Melting Point ]:
241-243ºC

[ Molecular Formula ]:
C14H13ClN4O4

[ Molecular Weight ]:
336.73000

[ Flash Point ]:
292.3ºC

[ Exact Mass ]:
336.06300

[ PSA ]:
134.02000

[ LogP ]:
4.31760

[ Vapour Pressure ]:
1.47E-12mmHg at 25°C

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

Articles

Peptide splicing in a double-sequence analogue of trypsin inhibitor SFTI-1 substituted in the P₁ positions by peptoid monomers.

Biopolymers 104 , 206-12, (2015)

Recently, we described a process of trypsin-assisted peptide splicing of analogs of trypsin inhibitor SFTI-1, that seems to be very similar to proteasome-catalyzed peptide splicing. Here, we show, for...

Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A.

FEBS Lett. 588(23) , 4487-96, (2015)

Cyclotides belong to the family of cyclic cystine-knot peptides and have shown promise as scaffolds for protein engineering and pharmacological modulation of cellular protein activity. Cyclotides are ...

Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates.

J. Med. Chem. 29 , 514, (1986)

The aryl 4-guanidinobenzoate, 4'-nitrophenyl 4-guanidinobenzoate (NPGB), is a potent inhibitor of sperm acrosin, an enzyme with an essential function in the fertilization process. NPGB prevents fertil...


More Articles


Related Compounds

  • 4-NITROPHENYL-4-MORPHOLINOPHOSPHONOCHLORIDATE
  • (4-nitrophenyl) 4-methylbenzoate
  • 4-nitrophenyl 4-cyanophenyl thionocarbonate
  • (4-nitrophenyl) 4-propylbenzoate
  • (4-nitrophenyl) 4-hexoxybenzoate
  • (4-nitrophenyl) 4-chloro-3-nitrobenzenesulfonate
  • 5-Methyl-2-(piperidin-4-ylmethyl)pyridine
  • 1-(2-cyclopropylphenyl)-N-methylmethanamine
  • 6-chloro-N-[(3-chlorophenyl)methyl]-2-methylpyrimidin-4-amine
  • 2-Pyridinamine, 5-(2,4,6-trimethoxyphenyl)-
  • 1-(3-Cyclopropylphenyl)ethan-1-amine
  • 3-Cyclopropyl-4-methoxybenzoic acid
  • N-[3-(dimethylamino)propyl]-1,2-dihydro-2-oxo-6-quinolinecarboxamide
  • 2-(Pentafluoro-l6-sulfanyl)benzamide
  • 5-Chloro-2-(pentafluoro-l6-sulfaneyl)benzamide
  • 2-(Ethanesulfonyl)pyrimidin-5-amine
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