3-(2,3-dimethylphenyl)-2-methylquinazolin-4-one

Names

[ CAS No. ]:
1915-79-3

[ Name ]:
3-(2,3-dimethylphenyl)-2-methylquinazolin-4-one

[Synonym ]:
B 191
Ro 353
3-<2.3-Dimethyl-phenyl>-2-methyl-3H-chinazolin-4-on

Chemical & Physical Properties

[ Density]:
1.14g/cm3

[ Boiling Point ]:
438.6ºC at 760 mmHg

[ Molecular Formula ]:
C17H16N2O

[ Molecular Weight ]:
264.32200

[ Flash Point ]:
219.1ºC

[ Exact Mass ]:
264.12600

[ PSA ]:
34.89000

[ LogP ]:
3.31090

[ Vapour Pressure ]:
6.82E-08mmHg at 25°C

[ Index of Refraction ]:
1.614

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA4146500
CHEMICAL NAME :
4(3H)-Quinazolinone, 2-methyl-3-(2,3-xylyl)-
CAS REGISTRY NUMBER :
1915-79-3
BEILSTEIN REFERENCE NO. :
0887483
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H16-N2-O
MOLECULAR WEIGHT :
264.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,688,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 17,616,1962

Related Compounds

  • 3-(2,3-dimethylphenyl)-2-methylquinazolin-4-one,hydrochloride
  • 3-(2,4-dimethylphenyl)-2-methylquinazolin-4-one,hydrochloride
  • 3-(2,6-dimethylphenyl)-2-methylquinazolin-4-one
  • 3-(2,5-dimethylphenyl)-2-methylquinazolin-4-one
  • 3-(2,3-dimethylphenyl)-2-hydrazinylquinazolin-4-one
  • 3-(2,3-dimethylphenyl)-2-hydroxy-chromen-4-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 2-(Chloromethyl)-5-(difluoromethyl)-3-(trifluoromethyl)pyridine-6-carboxaldehyde
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 4-Amino-6-(difluoromethyl)-5-hydroxypyridine-3-sulfonamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Ethyl 2-amino-2-[3-fluoro-5-(trifluoromethyl)phenyl]acetate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde