4(3H)-Quinazolinone, 5,6,7,8-tetrahydro-2-methyl-

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Names

[ CAS No. ]:
19178-21-3

[ Name ]:
4(3H)-Quinazolinone, 5,6,7,8-tetrahydro-2-methyl-

[Synonym ]:
2-Methyl-5,6,7,8-tetrahydro-3H-quinazolin-4-one
2-Methyl-5,6,7,8-tetrahydroquinazolin-4-ol
2-Methyl-5,6,7,8-tetrahydro-3H-chinazolin-4-on
5,6,7,8-tetrahydro-2-methyl-4-quinazolone

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
291.2ºC at 760 mmHg

[ Molecular Formula ]:
C9H12N2O

[ Molecular Weight ]:
164.20400

[ Flash Point ]:
129.9ºC

[ Exact Mass ]:
164.09500

[ PSA ]:
45.75000

[ LogP ]:
0.95710

[ Vapour Pressure ]:
0.00198mmHg at 25°C

[ Index of Refraction ]:
1.644

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA4252000
CHEMICAL NAME :
4(3H)-Quinazolinone, 5,6,7,8-tetrahydro-2-methyl-
CAS REGISTRY NUMBER :
19178-21-3
LAST UPDATED :
198602
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H12-N2-O
MOLECULAR WEIGHT :
164.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 2,231,1967

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-bromocyclohexene-1-carboxylic acid
  • Acetimidamide hydrochloride
  • 2-methyl-2,3,5,6,7,8-hexahydroquinazolin-4(1H)-one
  • Ethyl 2-oxocyclohexanecarboxylate
  • acetamidine
  • 7-bromo-7-fluorobicyclo[4.1.0]heptane

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-[4-(2-Hydroxyethyl)-1-piperazinyl]-5,6,7,8-tetrahydro-4(1H)-quinazolinone
  • 4-quinazolinol, 5,6,7,8-tetrahydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-
  • 4-quinazolinol, 5,6,7,8-tetrahydro-2-[4-(4-methoxyphenyl)-1-piperazinyl]-
  • [1]Benzothieno[2,3-d]pyrimidine-4(3H)-thione,5,6,7,8-tetrahydro-2-methyl-
  • 2,3-diamino-5,6,7,8-tetrahydroquinazolin-4-one
  • 3-(2-Cyclopentylethyl)-2-(2-hydroxyphenyl)-5,6,7,8-tetrahydro-4(3H)-quinazolinone
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine