Tipifarnib (R115777)

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Names

[ CAS No. ]:
192185-72-1

[ Name ]:
Tipifarnib (R115777)

[Synonym ]:
Zarnestra
6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
S1453_Selleck
tipifarnib
Tipifarnib (Zarnestra)
6-[(r)-amino(4-chlorophenyl)(1-methyl-1h-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1h)-one
2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
681.7±55.0 °C at 760 mmHg

[ Melting Point ]:
211-213ºC (dec.)

[ Molecular Formula ]:
C27H22Cl2N4O

[ Molecular Weight ]:
489.396

[ Flash Point ]:
366.1±31.5 °C

[ Exact Mass ]:
488.117065

[ PSA ]:
65.84000

[ LogP ]:
4.94

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.672

[ Storage condition ]:
-20?C Freezer

Related Compounds

  • Tipifarnib (S enantiomer)
  • 3,4-difluoro-N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)benzamide
  • 5-chloro-N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)thiophene-2-carboxamide
  • 2,4,6-trimethyl-N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)benzamide
  • N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide
  • N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)-2-(m-tolyloxy)acetamide
  • 2-(4-chlorophenyl)-N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)acetamide
  • N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)quinoxaline-2-carboxamide
  • N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)benzo[d]thiazole-2-carboxamide
  • N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)-4-(trifluoromethyl)benzamide
  • 7-methoxy-N-((1-(thiazol-2-yl)piperidin-3-yl)methyl)benzofuran-2-carboxamide
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