Tipifarnib (R115777)

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Names

[ CAS No. ]:
192185-72-1

[ Name ]:
Tipifarnib (R115777)

[Synonym ]:
Zarnestra
6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
S1453_Selleck
tipifarnib
Tipifarnib (Zarnestra)
6-[(r)-amino(4-chlorophenyl)(1-methyl-1h-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1h)-one
2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
681.7±55.0 °C at 760 mmHg

[ Melting Point ]:
211-213ºC (dec.)

[ Molecular Formula ]:
C27H22Cl2N4O

[ Molecular Weight ]:
489.396

[ Flash Point ]:
366.1±31.5 °C

[ Exact Mass ]:
488.117065

[ PSA ]:
65.84000

[ LogP ]:
4.94

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.672

[ Storage condition ]:
-20?C Freezer

Related Compounds

  • Tipifarnib (S enantiomer)
  • N-(Cyclopropylmethyl)-1-oxa-8-azaspiro[4.5]decane-3-carboxamide
  • N-(Pyridin-3-ylmethyl)-1-oxa-2,7-diazaspiro[4.5]dec-2-ene-3-carboxamide
  • N-Ethyl-N-methyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
  • 4-Propyl-1,8-dioxa-4,11-diazaspiro[5.6]dodecane
  • 11-(3-Fluorophenyl)-8-oxa-2,11-diazaspiro[5.6]dodecane
  • 4A-(methoxymethyl)octahydro-2H-pyrano[3,2-c]pyridine
  • 4A-((pyridin-2-yloxy)methyl)octahydro-2H-pyrano[3,2-c]pyridine
  • 1,4-Dimethyl-1,4,9-triazaspiro[5.5]undecan-5-one
  • N-(6-Azaspiro[2.5]octan-1-ylmethyl)methanesulfonamide
  • 2-(3-Methoxybenzyl)-2,7-diazaspiro[4.4]nonan-1-one
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