4-HYDROXY-3-METHOXYCINNAMIDE

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Names

[ CAS No. ]:
19272-90-3

[ Name ]:
4-HYDROXY-3-METHOXYCINNAMIDE

[Synonym ]:
Ferulic acid amide
4-hydroxy-3-methoxy-cinnamic acid amide
cinnamamide, 4-hydroxy-3-methoxy-
Ferulasaeure-amid
3-(4-Hydroxy-3-methoxyphenyl)acrylamide
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide
Ferulamid
4-Hydroxy-3-methoxy-zimtsaeure-amid
CINNAMAMIDE,4-HYDROXY-3-METHOXY
(2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylamide
4-Oxy-3-methoxy-zimtsaeure-amid
Ferulic amide
4-HYDROXY-3-METHOXYCINNAMIDE
2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
Ferulamide
feruloylamide
3-(4-Hydroxy-3-methoxyphenyl)-2-propenamide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
435.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H11NO3

[ Molecular Weight ]:
193.199

[ Flash Point ]:
217.0±28.7 °C

[ Exact Mass ]:
193.073898

[ PSA ]:
73.54000

[ LogP ]:
0.58

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.624

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GD7406000
CHEMICAL NAME :
Cinnamamide, 4-hydroxy-3-methoxy-
CAS REGISTRY NUMBER :
19272-90-3
LAST UPDATED :
199409
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H11-N-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 20,387,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 20,387,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>193 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 104,793,1984

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ferulic acid

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 4-HYDROXY-3-METHOXYCINNAMIDE
  • 4-Hydroxy-3-Methoxycinnamide
  • 4-Hydroxy-3-methoxyphenyl O-beta-D-(6'-O-syringate)glucopyraside
  • 4-hydroxy-3-methyl-4-phenyl-thiolan-2-one
  • 4-hydroxy-3-methoxybenzamide
  • 4-hydroxy-3-methylsulfanylbenzaldehyde
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • 4-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,3-dimethylpentanamido]butanoic acid