Benzamide,N,N-diethyl-2-hydroxy-

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Names

[ CAS No. ]:
19311-91-2

[ Name ]:
Benzamide,N,N-diethyl-2-hydroxy-

[Synonym ]:
o-Hydroxy-N,N-diethylbenzamide
2-hydroxy-N,N'-diethyl-benzamide
N,N-diethyl-o-hydroxybenzamide
EINECS 242-955-8
Salicyldiethylamide
N,N-Diethylsalicylamide
MFCD00010816
N,N-diethyl 2-hydroxybenzamide
Benzamide,N,N-diethyl-2-hydroxy
Salicylamide,N,N-diethyl

Chemical & Physical Properties

[ Density]:
1.497g/cm3

[ Boiling Point ]:
382.6ºC at 760 mmHg

[ Melting Point ]:
93-97ºC(lit.)

[ Molecular Formula ]:
C11H15NO2

[ Molecular Weight ]:
193.24200

[ Flash Point ]:
185.2ºC

[ Exact Mass ]:
193.11000

[ PSA ]:
40.54000

[ LogP ]:
1.87420

[ Vapour Pressure ]:
4.67E-06mmHg at 25°C

[ Index of Refraction ]:
1.656

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN7320000
CHEMICAL NAME :
Salicylamide, N,N-diethyl-
CAS REGISTRY NUMBER :
19311-91-2
BEILSTEIN REFERENCE NO. :
2835473
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C11-H15-N-O2
MOLECULAR WEIGHT :
193.27
WISWESSER LINE NOTATION :
QR BVN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
580 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,450,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,450,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
850 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 8,237,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26;S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VN7320000

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • N,N-DIETHYLBENZAMIDE
  • Diethylamine
  • Benzoyl chloride,2-hydroxy-
  • 2-(Trifluoromethyl)phenol
  • Benzamide,N,N-diethyl-2-methoxy-
  • DIETHYL-CARBAMIC ACID PHENYL ESTER
  • o-anisoyl chloride
  • Sodium Salicylate
  • Diethylcarbamic chloride
  • Phenyl salicylate

DownStream

  • 2-Propionylphenol
  • N,N-diethyl-2-trimethylsilyloxybenzamide
  • (2-propanoylphenyl) acetate
  • 2-(diethylaminomethyl)phenol
  • 1-(2-Methoxyphenyl)propan-1-one
  • Benzamide,N,N-diethyl-2-methoxy-

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • Benzamide,N,N-diethyl-2-hydroxy-4-methoxy
  • Benzamide,N,N-diethyl-2-hydroxy-5-methoxy
  • Benzamide,N,N-diethyl-2-hydroxy-3-methoxy
  • Benzamide,N,N-diethyl-2-methyl-
  • Benzamide,N,N-diethyl-2-methoxy-
  • Benzamide, N,N-diethyl-2,3-dihydroxy- (9CI)
  • tert-butyl N-[7-(methoxyimino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamate
  • tert-butyl N-[5-cyano-3-(prop-2-en-1-yl)-2-sulfanylidene-2,3-dihydro-1,3-thiazol-4-yl]carbamate
  • 2-{[(Tert-butoxy)carbonyl][3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid
  • benzyl N-[2-(2-fluoro-4-sulfamoylphenoxy)ethyl]-N-methylcarbamate
  • tert-butyl N-[2-(2,4-difluorophenyl)-1-(1-methyl-1H-1,2,4-triazol-5-yl)ethyl]-N-(2-hydroxyethyl)carbamate
  • 2-{Benzyl[(benzyloxy)carbonyl]amino}-4-methyl-1,3-thiazole-5-carboxylic acid
  • 2-{Benzyl[(benzyloxy)carbonyl]amino}-5-methyl-1,3-thiazole-4-carboxylic acid
  • benzyl N-(5-{[(4-cyanophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-yl)carbamate
  • 3-{[(Benzyloxy)carbonyl][(1-methylpiperidin-4-yl)methyl]amino}benzoic acid
  • 4-{[(Tert-butoxy)carbonyl][4-(5-methylthiophen-2-yl)-1,3-thiazol-2-yl]amino}butanoic acid
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