Taurolidine
Suppliers
Names
[ CAS No. ]:
19388-87-5
[ Name ]:
Taurolidine
[Synonym ]:
4,4'-Methylenebis(tetrahydro-1,2,4-thiadiazine) 1,1,1',1'-tetraoxide
4,4'-methanediylbis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide
2H-1,2,4-Thiadiazine, 4,4'-methylenebis[tetrahydro-, 1,1,1',1'-tetraoxide
4,4'-Methylenebis(tetrahydro-1,2,4-sulfadiazine 1,1-dioxide)
4,4'-Methylenebis(perhydro-1,2,4-thiadiazine 1,1-dioxide)
Bis(1,1-dioxoperhydro-1,2,4-thiadiazin-4-yl)methane
4,4'-Methylenebis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide
Taurolin
Taurolidine
Tauroline
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
471.2±55.0 °C at 760 mmHg
[ Melting Point ]:
156ºC
[ Molecular Formula ]:
C7H16N4O4S2
[ Molecular Weight ]:
284.356
[ Flash Point ]:
238.8±31.5 °C
[ Exact Mass ]:
284.061310
[ PSA ]:
115.58000
[ LogP ]:
-2.55
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.564
MSDS
Safety Information
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Int. J. Colorectal Dis. 29(11) , 1339-48, (2014)
The taurine derivative taurolidine (TRD) exerts anti-neoplastic effects in a variety of tumor models. On the other hand, TRD at low doses was shown to reduce cell-cell adhesion, a prerequisite for met...
Pediatr. Blood Cancer 60(8) , 1292-8, (2013)
To determine if the catheter lock taurolidine can reduce the number of catheter-related bloodstream infections (CRBSI) in pediatric cancer patients with tunneled central venous catheters (CVC).During ...
J. Pediatr. Hematol. Oncol. 36(4) , e219-23, (2014)
Neuroblastoma is a common pediatric solid tumor with poor outcome for metastatic disease. Thus, novel therapeutic options are of main interest. The anti-neoplastic properties of taurolidine have been ...