POLYOXIN B

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Names

[ CAS No. ]:
19396-06-6

[ Name ]:
POLYOXIN B

[Synonym ]:
piomycin
Polyoxin AL
POLYXIN

Chemical & Physical Properties

[ Density]:
1.774 g/cm3

[ Molecular Formula ]:
C17H25N5O13

[ Molecular Weight ]:
507.40600

[ Exact Mass ]:
507.14500

[ PSA ]:
309.98000

[ Index of Refraction ]:
1.669

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BA2927000
CHEMICAL NAME :
Allofuranuronic acid, 5-(2-amino-2-deoxy-L-xylonamido)-1,5-dideoxy-1-(3,4-d ihydro-5- (hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl)-, monocarbamate (ester), beta-D-
CAS REGISTRY NUMBER :
19396-06-6
LAST UPDATED :
199204
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C17-H25-N5-O13
MOLECULAR WEIGHT :
507.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14665 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C244,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,696,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15638 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C244,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (40),32,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,245,1981

Safety Information

[ HS Code ]:
2934999031

Precursor & DownStream

Precursor

  • 5-Hydroxymethyluracil
  • methyl (5-azido-5-deoxy-1,2,3-tri-O-acetyl-D-allofuranosid)uronate
  • Pyrimidine, 2,4-bis[(trimethylsilyl)oxy]-5-[[(trimethylsilyl)oxy]methy l]-

DownStream

Customs

[ HS Code ]: 2934999031


Related Compounds

  • Polyoxin B,mixted with oxine-copper
  • Coralloidin B
  • Benzo[b]selenophen-3(2H)-one
  • dubioside B
  • box B-binding factor 2
  • chloropolysporin B
  • N1-(3-chloro-4-methylphenyl)-N2-(1-tosyl-1,2,3,4-tetrahydroquinolin-7-yl)oxalamide
  • N-(7-hydroxy-5,6-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)furan-2-carboxamide
  • Ethyl 6-((4-aminophenyl)(methyl)amino)hexanoate
  • 4-((1H-Pyrazol-1-yl)methoxy)benzaldehyde
  • Fmoc-4-(2-methoxyphenyl)-DL-phenylalanine
  • 2-(2-(tert-Butoxy)-2-oxoethyl)pentanoic acid
  • 2-((Tert-butoxycarbonyl)methyl)pent-4-enoic acid
  • 2,4-Dihydro-4-methyl-5-(4-methyl-5-thiazolyl)-3H-1,2,4-triazole-3-thione
  • (7-Chloro-1H-benzo[d]imidazol-2-yl)methanamine
  • 1-(2-((3-(4-chlorophenyl)-4-oxo-4H-chromen-7-yl)oxy)ethyl)piperidine-4-carboxamide
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