1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin

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Names

[ CAS No. ]:
19408-74-3

[ Name ]:
1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin

[Synonym ]:
PCDD 70
1,2,3,7,8,9-Hexachlorodibenzodioxin
1,2,3,7,8,9-HxCDD
Dibenzo-p-dioxin,1,2,3,7,8,9-hexachloro
1,2,3,7,8,9-hexachlorinated dibenzodioxin
1,2,3,7,8,9-H6CDD
D 70
1,2,3,7,8,9-hexachlorooxanthrene
1,2,3,6,7,8,9-hexachloro dibenzo-p-dioxin
HxCDD

Chemical & Physical Properties

[ Density]:
1.777g/cm3

[ Boiling Point ]:
478ºC at 760mmHg

[ Molecular Formula ]:
C12H2Cl6O2

[ Molecular Weight ]:
390.86100

[ Flash Point ]:
182.9ºC

[ Exact Mass ]:
387.81900

[ PSA ]:
18.46000

[ LogP ]:
7.50500

[ Vapour Pressure ]:
7.72E-09mmHg at 25°C

[ Index of Refraction ]:
1.666

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP3310000
CHEMICAL NAME :
Dibenzo-p-dioxin, 1,2,3,7,8,9-hexachloro-
CAS REGISTRY NUMBER :
19408-74-3
BEILSTEIN REFERENCE NO. :
1353896
LAST UPDATED :
199806
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H2-Cl6-O2
MOLECULAR WEIGHT :
390.84
WISWESSER LINE NOTATION :
T C666 BO IOJ DG EG FG LG MG NG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1440 mg/kg
TOXIC EFFECTS :
Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
60 ug/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - mouse Fibroblast
DOSE/DURATION :
120 pmol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1485,1987 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997

Safety Information

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
I

[ Hazard Class ]:
6.1(a)

[ HS Code ]:
2932999060

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Chlorobenzene
  • Tetrachloroethylene
  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin
  • Dimethachlor
  • 2,4,5-Trichlorophenol
  • potassium salt of 2,3,4,5-tetrachlorophenol

DownStream

Customs

[ HS Code ]: 2932999060

[ Summary ]:
2932999060. Dioxin,Furan(polychorinated dibenzo-p-dioxines,polychlorinated dibenzofurans). VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods). MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 1,2,3,7,8,9-Hexachlorodibenzo-P-Dioxin (13C12, 99%) 50 Ug/Ml In Nonane:Toluene (80:20)
  • 1,2,3,6,8,9-hexachlorodibenzo-p-dioxin
  • 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin
  • 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin
  • 1,2,3,4,7,8-Hexachlorodibenzo-P-Dioxin (13C12, 99%) 50 Ug/Ml In Nonane
  • 1,2,3,7,8,9-HEXABROMODIBENZO-PARA-DIOXIN