2-[2-[2-[2-(oxiran-2-ylmethoxy)ethoxy]ethoxy]ethoxymethyl]oxirane

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Names

[ CAS No. ]:
1954-28-5

[ Name ]:
2-[2-[2-[2-(oxiran-2-ylmethoxy)ethoxy]ethoxy]ethoxymethyl]oxirane

[Synonym ]:
Ethoglucide
Etoglucide
Etoglucidum [INN-Latin]
Triethylene glycol diglycidyl ether
1,2-bis-(2-oxiranylmethoxy-ethoxy)-ethane
Ethoglucid
Diglycidyltriethylene glycol
Etoglucide [INN-French]
Epodyl
Etoglucid

Chemical & Physical Properties

[ Density]:
1.157g/cm3

[ Boiling Point ]:
356.4ºC at 760mmHg

[ Molecular Formula ]:
C12H22O6

[ Molecular Weight ]:
262.29900

[ Flash Point ]:
145ºC

[ Exact Mass ]:
262.14200

[ PSA ]:
61.98000

[ Vapour Pressure ]:
6.02E-05mmHg at 25°C

[ Index of Refraction ]:
1.474

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XF0700000
CHEMICAL NAME :
2,2'-(2,5,8,11-Tetraoxa-1,12-dodecane diyl)bisoxirane
CAS REGISTRY NUMBER :
1954-28-5
BEILSTEIN REFERENCE NO. :
4311213
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H22-O6
MOLECULAR WEIGHT :
262.34
WISWESSER LINE NOTATION :
T3OTJ B1O2O2O2O1- BT3OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3800 mg/kg/4W
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
300 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 111,99,1983 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,209,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,209,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ WGK Germany ]:
1

[ HS Code ]:
2910900090

Synthetic Route

Precursor & DownStream

Precursor

  • Epichlorohydrin
  • Triethylene glycol

DownStream

  • 1-(hexylamino)-3-[2-[2-[2-[3-(hexylamino)-2-hydroxypropoxy]ethoxy]ethoxy]ethoxy]propan-2-ol

Customs

[ HS Code ]: 2910900090

[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%