Wortmannin
Suppliers
Names
[ CAS No. ]:
19545-26-7
[ Name ]:
Wortmannin
[Synonym ]:
EINECS 214-538-0
Wartmannin
MFCD00133927
3H-Furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione, 11-(acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-, (1S,6bR,9aS,11R,11bR)-
(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE
Wortmannin
SL-2052
Antibiotic SL-2052
(1S,6bR,9aS,11R,11bR)-1-(Methoxymethyl)-9a,11b-dimethyl-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3H-furo[4,3,2-de]indeno[4,5-h]isochromen-11-yl acetate
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
615.6±55.0 °C at 760 mmHg
[ Melting Point ]:
234-240ºC
[ Molecular Formula ]:
C23H24O8
[ Molecular Weight ]:
428.432
[ Flash Point ]:
326.1±31.5 °C
[ Exact Mass ]:
428.147125
[ PSA ]:
109.11000
[ LogP ]:
0.81
[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C
[ Index of Refraction ]:
1.591
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
DMSO: soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CB9641000
- CHEMICAL NAME :
- Antibiotic SL-2052
- CAS REGISTRY NUMBER :
- 19545-26-7
- BEILSTEIN REFERENCE NO. :
- 0067676
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C23-H24-O8
- MOLECULAR WEIGHT :
- 428.47
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 30,135,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,168,1981
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300-H310-H330
[ Precautionary Statements ]:
P260-P264-P280-P284-P302 + P350-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+: Very toxic;T: Toxic;
[ Risk Phrases ]:
R26/27/28
[ Safety Phrases ]:
28-36/37-45
[ RIDADR ]:
UN 3462
[ WGK Germany ]:
3
[ RTECS ]:
CB9641000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1
Synthetic Route
Precursor & DownStream
Precursor
DownStream
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