Ethanol,2-[[(5-nitro-2-furanyl)methylene]oxidoamino]-

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Names

[ CAS No. ]:
19561-70-7

[ Name ]:
Ethanol,2-[[(5-nitro-2-furanyl)methylene]oxidoamino]-

[Synonym ]:
Ethanol,N-oxide
Nifuratrone
2-Hydroxy-N-(5-nitrofurfuryliden)ethanamin-N-oxid
Nifuratrona [INN-Spanish]
Nifuratronum [INN-Latin]
Nifuratrone [USAN:INN]

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Boiling Point ]:
412ºC at 760mmHg

[ Molecular Formula ]:
C7H8N2O5

[ Molecular Weight ]:
200.14900

[ Flash Point ]:
203ºC

[ Exact Mass ]:
200.04300

[ PSA ]:
107.94000

[ LogP ]:
1.15570

[ Vapour Pressure ]:
1.59E-07mmHg at 25°C

[ Index of Refraction ]:
1.618

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QX8530000
CHEMICAL NAME :
Nitrone, N-(2-hydroxyethyl)-alpha-(5-nitro-2-furyl)-
CAS REGISTRY NUMBER :
19561-70-7
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C7-H8-N2-O5
MOLECULAR WEIGHT :
200.17
WISWESSER LINE NOTATION :
T5OJ BNW E1UNO&2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
518 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
417 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
522 gm/kg/46W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
500 nmol/well
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 34,2266,1974

Safety Information

[ HS Code ]:
2932190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Nitrofuraldehyde

DownStream

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 5-(4-Butoxy-[1,2,5]thiadiazol-3-yl)-1,2-dimethyl-1,2,3,6-tetrahydro-pyridine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide