3-Oxidido 17-alpha-ethynyl 17-beta-hydroxy estra-4,9,11-triene [French ]
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Names
[ CAS No. ]:
19636-23-8
[ Name ]:
3-Oxidido 17-alpha-ethynyl 17-beta-hydroxy estra-4,9,11-triene [French ]
[Synonym ]:
R 2010 oxime
Oxime,17-hydroxy-19-norpregna-4,9,11-trien-20-yn-3-one
So 57
Chemical & Physical Properties
[ Density]:
1.244g/cm3
[ Boiling Point ]:
533.233ºC at 760 mmHg
[ Molecular Formula ]:
C20H23NO2
[ Molecular Weight ]:
309.40200
[ Flash Point ]:
358.8ºC
[ Exact Mass ]:
309.17300
[ PSA ]:
52.82000
[ LogP ]:
3.59380
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.643
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RC8960090
- CHEMICAL NAME :
- 19-Norpregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-, oxime, (17-alpha)-
- CAS REGISTRY NUMBER :
- 19636-23-8
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H23-N-O2
- MOLECULAR WEIGHT :
- 309.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #4826M ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 mg/kg
- SEX/DURATION :
- female 6-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- SCYYDZ Shengzhi Yu Biyun. Reproduction and Contraception. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) 1980- Volume(issue)/page/year: 10(3),67,1990