3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE

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Names

[ CAS No. ]:
19652-13-2

[ Name ]:
3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE

[Synonym ]:
5-amino-3-(4-methoxylphenyl)-1-phenyl-1H-pyrazole
5-(4-methoxy-phenyl)-2-phenyl-2H-pyrazol-3-ylamine
3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-YLAMINE
3-(4-methoxyphenyl)-1-phenylpyrazole-5-ylamine
5-(4-Methoxy-phenyl)-2-phenyl-2H-pyrazol-3-ylamin
5-Amino-3-(4-methoxyphenyl)-1-phenylpyrazole
3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE
MFCD00197061

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
483.568ºC at 760 mmHg

[ Melting Point ]:
192-196ºC(lit.)

[ Molecular Formula ]:
C16H15N3O

[ Molecular Weight ]:
265.31000

[ Flash Point ]:
246.254ºC

[ Exact Mass ]:
265.12200

[ PSA ]:
53.07000

[ LogP ]:
3.71130

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.626

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phenylhydrazine
  • 3-(4-Methoxyphenyl)-3-oxopropanenitrile
  • Methyl anisate
  • 5-(p-methoxyphenyl)dithia[1,2]cyclopenten-3-one
  • Anethole trithione

DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-α and IL-6 inhibitors

Bioorg. Med. Chem. 16 , 7167-76, (2008)

Three different series of pyrazolo[3,4- b]pyridines were synthesized and evaluated for their anti-inflammatory activity against TNF-α and IL-6. Several compounds showed promising IL-6 inhibitory activ...

Approaches towards the synthesis of 5-aminopyrazoles. Aggarwal R, et al.

Beilstein J. Org. Chem. 7(1) , 179-197, (2011)


More Articles

Related Compounds

  • 5-Iodo-6-methyl-2,3-dihydro-1H-inden-1-one
  • Benzenepropanoic acid, 5-iodo-2-methyl
  • 3,4-Bis(dichloromethylidene)-1-phenylpyrrolidine-2,5-dione
  • (3-Methanesulfonylphenyl)methanethiol
  • 4-Methoxy-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyrimidine
  • 4-Chloro-7-fluoroquinazolin-6-ol
  • 1-Cyclopropyl-5-hydroxy-2-methyl-1H-indole-3-carboxylic acid
  • 1-(4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)-3,3-dimethylbutan-2-one
  • 3-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide
  • (S)-4,4-Difluoro-2-methylpyrrolidine hydrochloride
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