3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE

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Names

[ CAS No. ]:
19652-13-2

[ Name ]:
3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE

[Synonym ]:
5-amino-3-(4-methoxylphenyl)-1-phenyl-1H-pyrazole
5-(4-methoxy-phenyl)-2-phenyl-2H-pyrazol-3-ylamine
3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-YLAMINE
3-(4-methoxyphenyl)-1-phenylpyrazole-5-ylamine
5-(4-Methoxy-phenyl)-2-phenyl-2H-pyrazol-3-ylamin
5-Amino-3-(4-methoxyphenyl)-1-phenylpyrazole
3-(4-METHOXYPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE
MFCD00197061

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
483.568ºC at 760 mmHg

[ Melting Point ]:
192-196ºC(lit.)

[ Molecular Formula ]:
C16H15N3O

[ Molecular Weight ]:
265.31000

[ Flash Point ]:
246.254ºC

[ Exact Mass ]:
265.12200

[ PSA ]:
53.07000

[ LogP ]:
3.71130

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.626

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phenylhydrazine
  • 3-(4-Methoxyphenyl)-3-oxopropanenitrile
  • Methyl anisate
  • 5-(p-methoxyphenyl)dithia[1,2]cyclopenten-3-one
  • Anethole trithione

DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-α and IL-6 inhibitors

Bioorg. Med. Chem. 16 , 7167-76, (2008)

Three different series of pyrazolo[3,4- b]pyridines were synthesized and evaluated for their anti-inflammatory activity against TNF-α and IL-6. Several compounds showed promising IL-6 inhibitory activ...

Approaches towards the synthesis of 5-aminopyrazoles. Aggarwal R, et al.

Beilstein J. Org. Chem. 7(1) , 179-197, (2011)


More Articles

Related Compounds

  • 3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol
  • 6-[5-(4-methoxyphenyl)-2-phenyl-1H-pyrazol-3-ylidene]cyclohexa-2,4-dien-1-one
  • 3-(4-Methoxyphenyl)-1-methyl-1H-pyrazol-5-amine
  • 3-(4-Cyclohexylphenyl)-1-phenyl-1H-pyrazol-5-amine
  • 3-(4-Butylphenyl)-1-phenyl-1H-pyrazol-5-amine
  • 3-(4-FLUOROPHENYL)-1-PHENYL-1H-PYRAZOL-5-AMINE
  • 1-[(1S,5S)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl]cyclopropane-1-carbonitrile
  • N-[(1-benzylpiperidin-2-yl)methyl]hydroxylamine
  • 1-[6-(Pyrrolidin-1-yl)pyridin-3-yl]ethane-1,2-diol
  • O-{[1-(1H-imidazol-5-yl)cyclopropyl]methyl}hydroxylamine
  • 1-(3,5-Dimethoxy-4-methylphenyl)cyclopropane-1-carbonitrile
  • 1-(trimethyl-1H-pyrazol-4-yl)cyclobutane-1-carbonitrile
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2S)-2-{[(tert-butoxy)carbonyl]amino}butanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2S)-2-methanesulfonamido-3-methylbutanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-[(2-oxo-1,2-dihydropyridin-1-yl)methyl]furan-2-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]propanoate
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