4-hydroxy-7-methoxy-3-phenoxychromen-2-one

Names

[ CAS No. ]:
19725-96-3

[ Name ]:
4-hydroxy-7-methoxy-3-phenoxychromen-2-one

[Synonym ]:
3-Phenoxy-4-hydroxy-7-methoxycumarin
3-Phenoxy-4-hydroxy-7-methoxycoumarin
2H-1-Benzopyran-2-one,4-hydroxy-7-methoxy-3-phenoxy
4-hydroxy-7-methoxy-3-phenoxy-chromen-2-one
4-hydroxy-7-methoxy-3-phenoxy-coumarin
4-Hydroxy-7-methoxy-3-phenoxy-cumarin

Chemical & Physical Properties

[ Density]:
1.396g/cm3

[ Boiling Point ]:
408.2ºC at 760 mmHg

[ Molecular Formula ]:
C16H12O5

[ Molecular Weight ]:
284.26300

[ Flash Point ]:
151ºC

[ Exact Mass ]:
284.06800

[ PSA ]:
68.90000

[ LogP ]:
3.29950

[ Vapour Pressure ]:
2.15E-07mmHg at 25°C

[ Index of Refraction ]:
1.65

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ3100100
CHEMICAL NAME :
2H-1-Benzopyran-2-one, 4-hydroxy-7-methoxy-3-phenoxy-
CAS REGISTRY NUMBER :
19725-96-3
BEILSTEIN REFERENCE NO. :
1258750
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H12-O5
MOLECULAR WEIGHT :
284.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,470,1991

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • α-phenoxy-2-hydroxy-4-methoxyactophenone
  • Ethyl carbonate

DownStream

Related Compounds

  • 4-Hydroxy-7-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one
  • 4-HYDROXY-7-METHOXY-3-PHENYLCOUMARIN 9&
  • 6-ethyl-4-hydroxy-7-methoxy-3-nitrochromen-2-one
  • (3S)-4-hydroxy-7-methoxy-3-(4-methoxyphenyl)-3H-quinolin-1-ium-2-one
  • 2-hydroxy-7-methoxy-3-(3-methoxyphenoxy)chromen-4-one
  • 7-methoxy-3-phenoxychromen-2-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Tert-butyl 4-(2-methoxy-2-oxo-1-(6-(pyridin-2-ylamino)pyridin-2-yl)ethyl)piperidine-1-carboxylate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-[1-(Hydroxymethyl)cycloheptyl]cyclopentan-1-ol
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4-[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-methylpentanoic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde