2-Methyl-3-nitrobenzoic acid

Suppliers

Names

[ CAS No. ]:
1975-50-4

[ Name ]:
2-Methyl-3-nitrobenzoic acid

[Synonym ]:
2-methyl-3-nitro-benzoic acid
3-Nitro-o-toluic Acid
Benzoic acid,2-methyl-3-nitro
EINECS 217-826-4
2-Methyl-3-nitrobenzoic acid
3-Nitro-2-methyl benzoic acid
2-Methyl-nitrobenzoic acid
MFCD00007160
3-Nitro-2-Toluic Acid
Benzoic acid, 2-methyl-3-nitro-
2-methyl-3-nitro-benzoicaci
3-nitro-2-Methyl benzoate

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
337.1±30.0 °C at 760 mmHg

[ Melting Point ]:
182-184 °C(lit.)

[ Molecular Formula ]:
C₈H₇NO₄

[ Molecular Weight ]:
181.145

[ Flash Point ]:
151.9±13.0 °C

[ Exact Mass ]:
181.037506

[ PSA ]:
83.12000

[ LogP ]:
2.28

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.601

[ Water Solubility ]:
<0.1 g/100 mL at 22 ºC

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Methylbenzoic acid
Methyl 2-methyl-3-nitrobenzoate
4-Fluorobenzaldehyde
2-Methyl-3-Nitrobenzonitrile
3-Nitro-2-xylene
2-Methyl-3-nitrobenzaldehyde
o-Tolunitrile
o-xylene
Paraxylic Acid
2-methyl-3-nitrobenzol-1-methandiol diacetate

DownStream

Methyl 2-methyl-3-nitrobenzoate
5-Nitro-1H-isochromen-1-one
3,4-dihydro-3-methoxy-5-nitroisocoumarin
METHYL 4-INDOLECARBOXYLATE
methyl 2-[(E)-2-(dimethylamino)ethenyl]-3-nitrobenzoate
Methyl 3-methoxy-2-methylbenzoate
Ropinirole
N,N-Dipropyl-2-methyl-3-nitrophenylethanamine
2-(2-(2-(Dipropylamino)ethyl)-6-nitrophenyl)acetic acid hydrochloride
2-methyl-3-nitro-N,N-dipropylbenzeneacetamide

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis of (2S)-2-amino-3-(1H-4-indolyl) propanoic acid, a novel tryptophan analog for structural modification of bioactive peptides. Fauq AH, et al.

Tetrahedron Asymmetry 9(23) , 4127-4134, (1998)

Palladium-catalyzed coupling of 2-bromoanilines with vinylstannanes. A regiocontrolled synthesis of substituted indoles. Krolski ME, et al.

J. Org. Chem. 53(6) , 1170-1176, (1988)