7-Amino-4-methylquinolin-2(1H)-one

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Names

[ CAS No. ]:
19840-99-4

[ Name ]:
7-Amino-4-methylquinolin-2(1H)-one

[Synonym ]:
7-amino-4-methyl-2-quinolinone
7-Amino-4-methylquinolin-2(1H)-one
4-methylcarbostyril
7-amino-4-methylhydroquinolin-2-one
EINECS 243-363-2
7-AMINO-4-METHYL-2-QUINOLINOL
7-Amino-4-methyl-2-quinolone
2(1H)-Quinolinone, 7-amino-4-methyl-
carbostiryl 124
7-Amino-4-methyl-2(1H)-quinolinone
carbostyril 124
7-Amino-4-methyl-2-hydroxyquinoline,7-Amino-4-methyl-2(1H)-quinolinone
Carbostyril 124 [7-Amino-4-methyl-2-quinolinol]
MFCD00134256

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
417.6±45.0 °C at 760 mmHg

[ Melting Point ]:
>275ºC (dec.)

[ Molecular Formula ]:
C10H10N2O

[ Molecular Weight ]:
174.199

[ Flash Point ]:
206.4±28.7 °C

[ Exact Mass ]:
174.079315

[ PSA ]:
59.14000

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.627

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl acetoacetate
  • m-Phenylenediamine
  • Z-Cys(Bzl)-Pro-NH-Meq
  • 7-(S-benzyl-L-cysteinyl-amido)-4-methyl-2-quinolinone hydrochloride
  • (4S,7S,10S,13S)-4-((S)-sec-butyl)-7-(2-carboxyethyl)-10-((R)-1-hydroxyethyl)-13-((4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)carbamoyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid

DownStream

  • 2(1H)-Quinolinone,7-hydroxy-4-methyl-
  • 2,6-dimethyl-9-methoxy-4H-pyrrolo(3,2,1-ij)quinolin-4-one
  • Carbostyril 124 N-Carboxymethyl Chloride
  • 4-Methylquinolin-7-amine
  • 2(1H)-Quinolinone,7-amino-1,4-dimethyl-(9CI)
  • N-(2-chloro-4-methyl-quinolin-7-yl)acetamide

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

A borane laser.

Nat. Commun. 6 , 5958, (2015)

Emission from electronically excited species forms the basis for an important class of light sources-lasers. So far, commercially available solution-processed blue-emitting laser materials are based o...

Amine-reactive forms of a luminescent diethylenetriaminepentaacetic acid chelate of terbium and europium: attachment to DNA and energy transfer measurements.

Bioconjug. Chem. 8(2) , 127-32, (1997)

An isothiocyanate form of a lanthanide chelate which is highly luminescent when bound to terbium or europium has been synthesized. The chelate consists of diethylenetriaminepentaacetic acid (DTPA) cov...

Fluorogenic substrates for chymotrypsin with 2-quinolinone derivatives as leaving groups.

Biol. Chem. Hoppe-Seyler 371(9) , 835-40, (1990)

Sensitive and convenient fluorometric assays for the determination of chymotrypsin have been developed by using the substrates Glt-Leu-Phe-NH-Meq, Glt-Phe-NH-FMeq and Glt-Leu-Phe-NH-FMeq, which have b...


More Articles

Related Compounds

  • 7-FLUORO-4-METHYLQUINOLIN-2(1H)-ONE
  • 7-amino-4-methoxymethyl-6-methylquinolin-2-one
  • 7-amino-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one
  • 7-amino-4-hydroxy-4-(trifluoromethyl)-3,4-dihydroquinolin-2(1H)-one
  • 7-amino-4,4-dimethyl-3,4-dihydro-1,8-naphthyridin-2(1H)-one
  • 7-METHYLQUINOLIN-2(1H)-ONE