Bazedoxifene

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Names

[ CAS No. ]:
198481-32-2

[ Name ]:
Bazedoxifene

[Synonym ]:
TSE-424
Bazedoxifene
1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-
1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-indol-5-ol
1-{4-[2-(Azepan-1-yl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol
Bazedoxifeno
1-{4-[2-(1-Azepanyl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol
1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-
Conbriza

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
694.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H34N2O3

[ Molecular Weight ]:
470.603

[ Flash Point ]:
373.8±31.5 °C

[ Exact Mass ]:
470.256958

[ PSA ]:
57.86000

[ LogP ]:
6.59

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-[4-(2-AZEPAN-1-YL-ETHOXY)-BENZYL]-5-BENZYLOXY-2-(4-BENZYLOXY-PHENYL)-3-METHYL-1H-INDOLE
  • Adipaldehyde
  • Azepane
  • 4-Hydroxybenzyl alcohol
  • 4'-(Benzyloxy)-2-bromopropiophenone
  • 3-methyl-5-phenylmethoxy-2-(4-phenylmethoxyphenyl)-1H-indole
  • 4-Benzyloxyaniline Hydrochloride

DownStream

Related Compounds

  • Bazedoxifene
  • Bazedoxifene-d4
  • Bazedoxifene HCl
  • Bazedoxifene N-Oxide
  • Bazedoxifene Acetate
  • Bazedoxifene-d4 N-Oxide
  • N-(1-cyano-1,2-dimethylpropyl)-2-[(4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
  • 2,5-dibromo-N-(1-phenylethyl)benzenesulfonamide
  • 5-(Quinolin-2-yl)picolinonitrile
  • 4-[2-(1H-benzimidazol-2-yl)ethynyl]aniline
  • (3S,5S,7S)-N-(2-{2-[2-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)ethoxy]ethoxy}ethyl)tricyclo[3.3.1.1~3,7~]decane-1-carboxamide
  • 2-(2-Phenyl-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)nicotinonitrile
  • N,4-Dimethyl-1H-pyrrole-2-carboxamide
  • 5-Chlorobiphenyl-3-carbonitrile
  • [2-[[3-Ethoxycarbonyl-4-methyl-5-(methylcarbamoyl)thiophen-2-yl]amino]-2-oxoethyl] 6-chloropyridine-3-carboxylate
  • 2-(6-Phenylpyridin-2-yl)aceticacid
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