N-(6-amino-3-methyl-2,4-dioxo-1H-pyrimidin-5-yl)acetamide

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Names

[ CAS No. ]:
19893-78-8

[ Name ]:
N-(6-amino-3-methyl-2,4-dioxo-1H-pyrimidin-5-yl)acetamide

[Synonym ]:
Acetamide,N-(4-amino-1,2,3,6-tetrahydro-1-methyl-2,6-dioxo-5-pyrimidinyl)
n-(6-amino-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide
5-acetamido-6-amino-3-methyluracil
AAMU
N-(4-Amino-1,2,3,6-tetrahydro-1-methyl-2,6-dioxo-5-pyrimidinyl)acetimide
5-Ammu
5-Acetylamino-6-amino-3-methyluracil

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Melting Point ]:
≥305ºC

[ Molecular Formula ]:
C7H10N4O3

[ Molecular Weight ]:
198.17900

[ Exact Mass ]:
198.07500

[ PSA ]:
109.98000

[ Index of Refraction ]:
1.606

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Amino-3-methyluracil
  • 6-Amino-2-methylthio-3-methyluracil
  • 6-amino-5-nitroso-3-methyluracil
  • 5,6-diamino-3-methyl-1H-pyrimidine-2,4-dione
  • Ethanoic anhydride
  • acetic acid

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Caffeine as a metabolic probe: validation of its use for acetylator phenotyping.

Clin. Pharmacol. Ther. 49(6) , 648-57, (1991)

The use of two caffeine metabolite ratios for acetylator phenotyping was validated by demonstrating concordance with two sulfamethazine tests in 178 unrelated healthy subjects. The caffeine metabolite...

An alternative test for acetylator phenotyping with caffeine.

Clin. Pharmacol. Ther. 42(5) , 509-13, (1987)

Previously published methods allow the determination of the genetically controlled acetylator status using caffeine as a test drug, based on the urinary excretion of a ring-opened metabolite of caffei...

Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.

J. Chromatogr. B. Biomed. Sci. Appl. 755(1-2) , 73-84, (2001)

Urinary metabolic ratios of caffeine are used in humans to assess the enzymatic activities of cytochrome P450 isoenzyme 1A2 (CYP1A2), xanthine oxidase (XO) and for phenotyping individuals for the bimo...


More Articles

Related Compounds

  • 2,4-Diamino-5-(difluoromethyl)nicotinic acid
  • 5-(Bromomethyl)-6-chloro-3-(difluoromethyl)pyridin-2-amine
  • 2-Chloro-6-(difluoromethyl)-3-nitro-5-(trifluoromethyl)pyridine
  • 6-Bromo-4-(difluoromethyl)-5-fluoropyridin-2-ol
  • 2-(2-Bromo-5-cyano-3-methylphenyl)acetic acid
  • (6-Chloro-[2,3'-bipyridin]-4-yl)methanol
  • 2-Chloro-6-(chloromethyl)-3-(difluoromethyl)isonicotinaldehyde
  • 2-Bromo-3-(bromomethyl)-4-fluoro-1-nitrobenzene
  • 2-Chloro-6-(difluoromethyl)-3-methoxypyridine-4-sulfonamide
  • 3-Chloro-5-methoxy-2-nitropyridine
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