6-Bromo-1,3-benzoxazol-2(3H)-one

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Names

[ CAS No. ]:
19932-85-5

[ Name ]:
6-Bromo-1,3-benzoxazol-2(3H)-one

[Synonym ]:
6-Bromobenzoksazolinon-2 [Polish]
2-BENZOXAZOLINONE,6-BROMO
2(3H)-Benzoxazolone, 6-bromo-
6-Bromo-1,3-benzoxazol-2(3H)-one
6-bromobenzoxazolinone
6-Bromo-2-benzoxazolone
6-Bromo-3H-benzooxazol-2-one
6-Bromo-2-benzoxazolinone
6-bromobenzo[d]oxazol-2(3H)-one
6-Bromo-2(3H)-benzoxazolone
2(3H)-Benzoxazolone,6-bromo
6-bromo-3H-1,3-benzoxazol-2-one
6-bromo-3H-benzoxazol-2-one

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Melting Point ]:
192-196ºC

[ Molecular Formula ]:
C7H4BrNO2

[ Molecular Weight ]:
214.016

[ Exact Mass ]:
212.942535

[ PSA ]:
46.00000

[ LogP ]:
2.07

[ Index of Refraction ]:
1.628

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM4960000
CHEMICAL NAME :
2-Benzoxazolinone, 6-bromo-
CAS REGISTRY NUMBER :
19932-85-5
BEILSTEIN REFERENCE NO. :
0135506
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H4-Br-N-O2
MOLECULAR WEIGHT :
214.03
WISWESSER LINE NOTATION :
T56 BMVOJ GE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),341,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
935 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),340,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
445 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),340,1964

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DM4960000

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Benzoxazolinone
  • 1,3-Dibromo-5,5-dimethylhydantoin
  • Salicylamide
  • 6-Bromo-1,3-benzoxazol-2-amine
  • N,2-Dihydroxybenzamide
  • aminophenol

DownStream

  • 2-Amino-5-bromophenol
  • 6-Bromo-2(3H)-benzoxazolethione
  • 6-Bromo-3-methylbenzo[d]oxazol-2(3H)-one
  • Triethylammonium chloride
  • 6-bromo-3-(2-(4-nitrophenyl)-2-oxoethyl)benzo[d]oxazol-2(3H)-one
  • 2-oxo-2,3-dihydro-1,3-benzoxazole-6-carbaldehyde

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 6-Bromo-5-fluoro-1,3-benzoxazol-2(3H)-one
  • 6-Bromo-3-methylbenzo[d]oxazol-2(3H)-one
  • 6-bromo-3-tritylbenzo[d]oxazol-2(3H)-one
  • 7-Bromo-1,3-benzoxazol-2(3H)-one
  • 6-amino-1,3-benzoxazol-2(3H)-one
  • 6-Bromo-1,3-benzoxazol-2-amine
  • 3-Amino-2-(2,6-difluoro-3-nitrophenyl)propan-1-ol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • ethyl 4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine-4-carboxylate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-amino-3-hydroxy-5-(1H-1,2,4-triazol-1-yl)pentanoic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde