5-methoxy-3-phenyl-1H-benzimidazol-2-one

Names

[ CAS No. ]:
19950-89-1

[ Name ]:
5-methoxy-3-phenyl-1H-benzimidazol-2-one

[Synonym ]:
2H-Benzimidazol-2-one,1,3-dihydro-6-methoxy-1-phenyl
1,3-Dihydro-6-methoxy-1-phenyl-2H-benzimidazol-2-one
6-methoxy-1-phenyl-1,3-dihydro-2h-benzimidazol-2-one
6-methoxy-1-phenyl-1,3-dihydro-benzoimidazol-2-one

Chemical & Physical Properties

[ Density]:
1.262g/cm3

[ Molecular Formula ]:
C14H12N2O2

[ Molecular Weight ]:
240.25700

[ Exact Mass ]:
240.09000

[ PSA ]:
47.28000

[ LogP ]:
2.73970

[ Index of Refraction ]:
1.626

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DE2276820
CHEMICAL NAME :
2H-Benzimidazol-2-one, 1,3-dihydro-6-methoxy-1-phenyl-
CAS REGISTRY NUMBER :
19950-89-1
BEILSTEIN REFERENCE NO. :
0659447
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H12-N2-O2
MOLECULAR WEIGHT :
240.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,321,1981

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 5-bromo-3-phenyl-1H-benzimidazol-2-one
  • 5-nitro-3-phenyl-1H-benzimidazol-2-one
  • 5,6-dichloro-3-phenyl-1H-benzimidazol-2-one
  • 5-chloro-4-methyl-3-phenyl-1H-benzimidazol-2-one
  • 6-Chloro-1,3-dihydro-1-phenyl-2H-benzimidazol-2-one
  • 5-Methoxy-3-phenyl-1H-pyrrolo[2,3-b]pyridine
  • (4-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)(isoxazol-5-yl)methanone
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 3-[1-(3,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-(3,4-dimethylphenyl)-1,2,4-thiadiazol-5-amine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2,2-Difluoro-3-Methylcyclopropanecarbonyl Chloride
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde