1-Bromo-4-chloro-2-fluorobenzene

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Names

[ CAS No. ]:
1996-29-8

[ Name ]:
1-Bromo-4-chloro-2-fluorobenzene

[Synonym ]:
4-Chloro-2-fluorobromobenzene
GR CF DE
1-bromo-2-fluoro-4-chloro-benzene
2-bromo-5-chloro-1-fluorobenzene
1-Bromo-4-chloro-2-fluorobenzene
2-bromo-5-chlorofluorobenzene
1-bromo-4-chloro-2-fluoro-benzene
2-fluoro-4-chlorobromobenzene
MFCD00079708
4-bromo-1-chloro-3-fluorobenzene
Benzene, 1-bromo-4-chloro-2-fluoro-
1-Bromo-4-chloro-2-fluoro benzene

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
187.3±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C6H3BrClF

[ Molecular Weight ]:
209.443

[ Flash Point ]:
67.1±21.8 °C

[ Exact Mass ]:
207.909058

[ LogP ]:
3.05

[ Vapour Pressure ]:
0.9±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.551

[ Water Solubility ]:
INSOLUBLE

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ WGK Germany ]:
3

[ HS Code ]:
2903999090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Chloro-2-fluoroaniline

DownStream

  • 4-Chloro-2-fluorophenylboronic acid
  • 1,4-Epoxynaphthalene, 6-chloro-1,4-dihydro
  • 3-Bromo-6-chloro-2-fluorobenzaldehyde

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis of benzonorbornadienes: regioselective benzyne formation.

J. Org. Chem. 66(9) , 2932-6, (2001)

This report details the synthesis of several benzonorbornadienes by Diels--Alder cycloaddition of cyclopentadiene derivatives with substituted benzyne intermediates, which were generated by low-temper...

Synthesis of substituted 2-cyanoarylboronic esters. Lysén M, et al.

J. Org. Chem. 71(6) , 2518-2520, (2006)

Exploiting the Differential Reactivities of Halogen Atoms: Development of a Scalable Route to IKK2 Inhibitor AZD3264 Murugan A, et al.

Org. Process Res. Dev. 18(5) , 646-651, (2014)


More Articles


Related Compounds

  • 1-Bromo-4-chloro-2,3,5,6-tetrafluorobenzene
  • 1-Bromo-4-chloro-3-methylthio-2-fluorobenzene
  • 1-Bromo-4-chloro-2-[(methoxymethoxy)methyl]benzene
  • 1-Bromo-4-chloro-2-nitrobenzene
  • 1-bromo-4-chloro-2-fluoro-3-methoxybenzene
  • 1-Bromo-4-chloro-2,5-difluorobenzene
  • N-{[1-(2-methoxyethyl)piperidin-4-yl]methyl}-3-(trifluoromethyl)benzamide
  • 4-chloro-N,N-diethylquinazolin-2-amine
  • N-((1-(2-methoxyethyl)piperidin-4-yl)methyl)-2-(trifluoromethyl)benzamide
  • 2-(Prop-2-yn-1-ylsulfonyl)pyridine
  • 1-Isopropylsulfonyl-2-aminobenzimidazole-6-boronic acid
  • 3-(5-(Trifluoromethyl)pyridin-2-yl)propanal
  • 4-(3-Pyridylethynyl)-2-thiazolylamine
  • (2E)-2-[(E)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethylidenehydrazinylidene]-1,2-diphenylethanone
  • 3-[5-(Trifluoromethyl)furan-2-yl]propanal
  • 4-Nitrophenyl methoxycarbamate
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