1-(PYRIDYL-3)-3,3-DIMETHYL TRIAZENE

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Names

[ CAS No. ]:
19992-69-9

[ Name ]:
1-(PYRIDYL-3)-3,3-DIMETHYL TRIAZENE

Chemical & Physical Properties

[ Density]:
1.07g/cm3

[ Boiling Point ]:
223.8ºC at 760 mmHg

[ Molecular Formula ]:
C7H10N4

[ Molecular Weight ]:
150.18100

[ Flash Point ]:
89.2ºC

[ Exact Mass ]:
150.09100

[ PSA ]:
40.85000

[ LogP ]:
1.64190

[ Vapour Pressure ]:
0.0943mmHg at 25°C

[ Index of Refraction ]:
1.556

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XY2275000
CHEMICAL NAME :
Triazene, 3,3-dimethyl-1-(m-pyridyl)-
CAS REGISTRY NUMBER :
19992-69-9
LAST UPDATED :
199106
DATA ITEMS CITED :
22
MOLECULAR FORMULA :
C7-H10-N4
MOLECULAR WEIGHT :
150.21
WISWESSER LINE NOTATION :
T6NJ CNUNN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
130 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Blood - leukemia
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Blood - leukemia
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg/44W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Brain and Coverings - tumors Peripheral Nerve and Sensation - peripheral nerve tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
100 mg/kg
SEX/DURATION :
female 14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
10 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
5 mg/kg
SEX/DURATION :
female 14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
50 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Rodent - hamster
DOSE/DURATION :
6250 ug/kg
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 158,269,1978 *** REVIEWS *** TOXICOLOGY REVIEW 32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York, Springer, 1975 Volume(issue)/page/year: -,49,1975

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Dimethylamine

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 1-[3]quinolyl-3,3-dimethyl-triazene
  • 1,3-Dihydro-3,3-dimethyl-6-hydroxy-2H-indol-2-one
  • 1-[(3,4-dichlorophenyl)methyl]-3,3-dimethyl-4-(4-nitrobenzoyl)quinoxalin-2-one
  • 1-(3,3-dimethyl-2-phenylcyclopropen-1-yl)-4-methoxybenzene
  • 3,3-dimethyl-1-(3-phenylsulfanyloxolan-2-yl)butan-2-one
  • [(Z)-[3-(3,3-dimethylazetidin-1-yl)-1-phenylpropylidene]amino] N-(4-methoxyphenyl)carbamate,hydrochloride
  • (S)-2-(N-(2-((tert-Butoxycarbonyl)amino)ethyl)-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)-3-(1-formyl-1H-indol-3-yl)propanoic acid
  • (R)-Pyrrolidin-2-ol hydrochloride
  • 6-chloro-N2-(6-methyl-1,3-benzothiazol-2-yl)pyridine-2,5-dicarboxamide
  • 6-Chloro-2-methyl-5-nitro-quinoxaline
  • (3S,4S)-N,N-dimethyl-4-(trifluoromethyl)pyrrolidine-3-sulfonamide
  • N-[[4-(2,2-difluoroethoxy)phenyl]methyl]cyclopropanamine
  • (4I+/-,5I+/-)-4,14-Dimethyl-9,19-cyclocholestane-3,24-dione
  • (E)-3-(2,4-dichloro-phenoxy)-but-2-enoic acid ethyl ester
  • 1-Bromo-2-[2-(3-methoxypropoxy)ethoxy]cyclohexane
  • 2,2-Dicyclopentylethan-1-amine