GMX1778

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Names

[ CAS No. ]:
200484-11-3

[ Name ]:
GMX1778

[Synonym ]:
N-Cyano-N'-(4-nitrophenyl)thiourea
N-cyano-N'-(6-(p-chlorophenoxy)hexyl)-N"-(4-pyridyl)guanidine
Thiourea,N-cyano-N'-(4-nitrophenyl)
Guanidine, N''-[6-(4-chlorophenoxy)hexyl]-N-cyano-N'-4-pyridinyl-
2-[6-(4-Chlorophenoxy)hexyl]-1-cyano-3-(4-pyridinyl)guanidine
GMX1778

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
526.9±58.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₂ClN₅O

[ Molecular Weight ]:
371.864

[ Flash Point ]:
272.4±32.3 °C

[ Exact Mass ]:
371.151276

[ PSA ]:
82.33000

[ LogP ]:
4.95

[ Appearance of Characters ]:
white solid

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.587

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P301 + P312 + P330-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Articles

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.

BMC Cancer 15 , 855, (2015)

Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in NAD(+) biosynthesis from nicotinamide, is one of the major factors regulating cancer cells metabolism and is considered a pr...