5-Hydroxy-2-adamantone

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Names

[ CAS No. ]:
20098-14-0

[ Name ]:
5-Hydroxy-2-adamantone

[Synonym ]:
Kemantane
5-Hydroxy-2-adamantanone
Tricyclo[3.3.1.1]decan-2-one, 5-hydroxy-, (1R,3S)-
5-Hydroxy-2-adamantone
5-hydroxyadamantan-2-one
Idramantone
4-oxoadamantol
MFCD00192211
1-hydroxyadamantane-4-one
(1R,3S,5s,7s)-5-Hydroxy-2-adamantanone
Adamantan-4-on-1-ol
kemantan

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
296.5±33.0 °C at 760 mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C10H14O2

[ Molecular Weight ]:
166.217

[ Flash Point ]:
124.9±18.0 °C

[ Exact Mass ]:
166.099380

[ PSA ]:
37.30000

[ LogP ]:
0.29

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.603

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914400090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • adamantanone
  • 5-Bromo-2-adamantanone
  • N-Hydroxyphthalimide
  • Sulfuric acid
  • 2-EPOXYMETHYLENEADAMANTANE
  • isopropylideneadamantane oxide
  • Adamantan-1-ol
  • Ethanoic anhydride
  • 2-Adamantanol

DownStream

  • 2-Adamantone-5-Carboxylic Acid
  • 5-Bromo-2-adamantanone
  • 5-Chloro-2-adamantanone
  • 1,4,4-trichloroadamantane
  • 4-Amino-1-adamantanol
  • 4-(2-oxopyrrolidin-1-yl)adamantane-1-carboxylic acid
  • 1-(5-hydroxy-2-adamantyl)pyrrolidin-2-one
  • Methyl 4-oxo-1-adamantanecarboxylate
  • AKOS BB-9596

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

[Interspecific differences in kemantan pharmacokinetics].

Eksp. Klin. Farmakol. 57(6) , 48-50, (1994)

The pharmacokinetics of the new immunostimulant kemantane, adamantane derivative, used in two species of animals (rats and rabbits) and man was studied. There were significant differences in the pharm...

[Kemantane pharmacokinetics in rats].

Biull. Eksp. Biol. Med. 110(11) , 501-3, (1990)

Pharmacokinetics of novel immunostimulating drug kamantane was studied by using gas-liquid chromatography in experiments on rats. It was found that kemantane biotransformed rapidly after oral administ...

[The clinical pharmacokinetics of kemantane].

Farmakol. Toksikol. 54(1) , 57-9, (1991)

The pharmacokinetics of a new Soviet-made immunostimulant kemantane, a derivative of adamantine, was studied by gas-liquid chromatography in patients with bronchial pathology. It was found that in the...


More Articles

Related Compounds

  • 5-hydroxy-2,4-dimethyl-2-(3-oxoocta-4,6-dienyl)furan-3-one
  • (5-hydroxy-2,3,5-triphenylcyclopenta-1,3-dien-1-yl)-phenylmethanone
  • 5-HYDROXY-2-NITROBENZYL ALCOHOL
  • 5-Hydroxy-2-methoxypyrimidine
  • 5-Hydroxy-2-Methylphenylboronic acid
  • 5-hydroxy-2-methoxypent-1-en-3-one
  • 5-Bromo-3-cyclopropoxypicolinonitrile
  • 3-(Aminomethyl)-N,N-dimethylpyridin-4-amine
  • tert-Butyl (S)-3-(acetamidomethyl)pyrrolidine-1-carboxylate
  • 3-Cyclopropoxy-4-(trifluoromethyl)picolinonitrile
  • 2-Cyano-3-cyclopropoxyisonicotinic acid
  • 3-Cyclopropoxy-4-methylpicolinonitrile
  • 1-((4-(Dimethylamino)pyrimidin-2-yl)methyl)-3-(2-ethoxyphenyl)urea
  • N-(2-Cyano-3-cyclopropoxypyridin-4-YL)methanesulfonamide
  • 1-(2-Chlorophenyl)-3-(4-(3-methoxypiperidin-1-yl)phenyl)urea
  • 3-Tert-butyl-4-cyclopropoxypicolinonitrile
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