D(-)-Norvaline

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Names

[ CAS No. ]:
2013-12-9

[ Name ]:
D(-)-Norvaline

[Synonym ]:
(R)-(−)-2-Aminopentanoic acid
D-Nva
H-D-Nva-OH
D-2-amino-pentanoate
NORVALINE, D-
D-2-Aminopentanoic acid
D(-)-Norvaline
D-norVal-OH
D-Norvaline
(R)-2-Aminopentanoic acid,(R)-2-Aminovaleric acid
(R)-(-)-2-Aminopentanoic acid
Norvaline
MFCD00008097
(R)-2-Aminopentanoic acid
(2R)-2-aminopentanoic acid
(R)-2-Aminovaleric Acid
EINECS 217-936-2
(R)-norvaline
D-2-Aminovaleric acid
D-Ape

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
222.9±23.0 °C at 760 mmHg

[ Melting Point ]:
300ºC

[ Molecular Formula ]:
C5H11NO2

[ Molecular Weight ]:
117.146

[ Flash Point ]:
88.6±22.6 °C

[ Exact Mass ]:
117.078979

[ PSA ]:
63.32000

[ LogP ]:
0.38

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.464

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • D-alanine
  • 2-Oxovaleric acid
  • (R)-2-phthalimidopentanoic acid
  • DL-Norvaline
  • L-norvaline benzyl ester, hydrochloride

DownStream

  • N-[(Benzyloxy)carbonyl]norvaline
  • 2-[(2-aminoacetyl)amino]pentanoic acid
  • D(-)-Glutamic acid
  • 2-Oxovaleric acid
  • D-Norvalinol
  • boc-d-nva-oh
  • (s)-1,2-epoxypentane
  • 1-(4-methylphenyl)sulfonyl-2-propylaziridine

Articles

Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).

Bioorg. Med. Chem. 19 , 6409-18, (2011)

The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...


More Articles

Related Compounds

  • D-Norvaline, 3-ethyl-, methyl ester (9CI)
  • D-Norvaline, 3-hydroxy-, (3S)-rel-
  • D-Norvaline, 4-oxo- (9CI)
  • D-Norvaline, Methyl ester (hydrochloride)(1:1)
  • D-Norvaline, N-[(1,1-dimethylethoxy)carbonyl]-, Methyl ester
  • D-Norvaline, N-(aminocarbonyl)- (9CI)