Sodium 2-oxobutanoate

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Names

[ CAS No. ]:
2013-26-5

[ Name ]:
Sodium 2-oxobutanoate

[Synonym ]:
Butanoic acid, 2-oxo-, sodium salt (1:1)
Butanoic acid,2-oxo-,sodium salt
sodium 2-ketobutyric acid
SodiuM 2-Oxobutyrate
MFCD00064194
2-Oxobutanoic acid sodium salt
BUTYRIC ACID,2-OXO-,SODIUM SALT
2-oxobuttersaeure,natrium salz
Sodium 2-Ketobutyrate
EINECS 217-937-8
2-Oxobutyric Acid Sodium Salt
2-Ketobutyric Acid Sodium Salt
Sodium 2-oxobutanoate
2-oxobutyric acid,sodium salt
Alpha-Ketobutyric Acid Sodium Salt

Chemical & Physical Properties

[ Density]:
1.182g/cm3

[ Boiling Point ]:
177.8ºC at 760mmHg

[ Melting Point ]:
210°C

[ Molecular Formula ]:
C₄H₅NaO₃

[ Molecular Weight ]:
124.071

[ Flash Point ]:
65ºC

[ Exact Mass ]:
124.013641

[ PSA ]:
57.20000

[ Appearance of Characters ]:
powder | white

[ Vapour Pressure ]:
0.0331mmHg at 25°C

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ET5955900

CHEMICAL NAME :: Butyric acid, 2-oxo-, sodium salt

CAS REGISTRY NUMBER :: 2013-26-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H5-O3.Na

MOLECULAR WEIGHT :: 124.08

WISWESSER LINE NOTATION :: OVV2 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2960 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 42,221,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9819 No. of Facilities: 147 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 2044 (estimated) No. of Female Employees: 1461 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
ET5955900

[ HS Code ]:
2918300090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Kinetic resolution of 2-hydroxybutanoate racemic mixtures by NAD-independent L-lactate dehydrogenase.

Bioresour. Technol. 102(7) , 4595-9, (2011)

Optically active D-2-hydroxybutanoate is an important building block intermediate for medicines and biodegradable poly(2-hydroxybutanoate). Kinetic resolution of racemic 2-hydroxybutanoate may be a gr...

Transaminase-catalyzed asymmetric synthesis of L-2-aminobutyric acid from achiral reactants.

Biotechnol. Lett. 31 , 1595-1599, (2009)

Asymmetric synthesis of an unnatural amino acid was demonstrated by omega-transaminase from Vibrio fluvialis JS17. L-2-Aminobutyric acid was synthesized from 2-oxobutyric acid and benzylamine with an ...

Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine.

Proc. Natl. Acad. Sci. U. S. A. 107(14) , 6234-9, (2010)

The dramatic increase in healthcare cost has become a significant burden to the world. Many patients are denied the accessibility of medication because of the high price of drugs. Total biosynthesis o...