GS-2989
Suppliers
Names
[ CAS No. ]:
2013-58-3
[ Name ]:
GS-2989
[Synonym ]:
meclocyline
Meclocycline(usan)
GS-2989
Meclocycline base
Chlormethylenecycline
Chemical & Physical Properties
[ Density]:
1.72g/cm3
[ Boiling Point ]:
716.4ºC at 760mmHg
[ Molecular Formula ]:
C22H21ClN2O8
[ Molecular Weight ]:
476.86
[ Flash Point ]:
387.1ºC
[ Exact Mass ]:
476.09900
[ PSA ]:
181.62000
[ LogP ]:
0.91580
[ Vapour Pressure ]:
0mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI7830000
- CHEMICAL NAME :
- 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octah ydro- 3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-
- CAS REGISTRY NUMBER :
- 2013-58-3
- LAST UPDATED :
- 198803
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C22-H21-Cl-N2-O8
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,1022,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,1022,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 425 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GICTAL Giornale Italiano di Chemioterapia. Italian Journal of Chemotherapy. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1954- Volume(issue)/page/year: 17,276,1970