5-FLUORO-2-HYDROXYPYRIMIDINE
Suppliers
Names
[ CAS No. ]:
2022-78-8
[ Name ]:
5-FLUORO-2-HYDROXYPYRIMIDINE
[Synonym ]:
5-Fluoro-pyrimidin-2-ol
5-Fluoropyrimidin-2-one
5-fluoro-2-pyrimidinone
5-Fluoro-2-pyrimidinol
2-Hydroxy-5-fluoropyrimidine
5-fluoro-2-pyrimidone
5-fluoro-1H-pyrimidin-2-one
5-Fluoro-2-hydroxypyridimine
5-Fluoropyrimidin-2(1H)-one
Chemical & Physical Properties
[ Density]:
1.46g/cm3
[ Melting Point ]:
170-174ºC
[ Molecular Formula ]:
C4H3FN2O
[ Molecular Weight ]:
114.07800
[ Exact Mass ]:
114.02300
[ PSA ]:
46.01000
[ LogP ]:
0.32130
[ Index of Refraction ]:
1.563
MSDS
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H315-H318-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
37/38-41
[ Safety Phrases ]:
26-39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933599090
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Invest. New Drugs 20(1) , 63-71, (2002)
5-Fluoro-Pyrimidinone (5FP) is an oral pro-drug of 5-Fluorouracil (5FU), and is converted to 5FU by hepatic aldehyde oxidase. Preclinically, 5FP demonstrated anti-tumor activity against colon 38 and P...