GW2974
Suppliers
Names
[ CAS No. ]:
202272-68-2
[ Name ]:
GW2974
[Synonym ]:
Lopac-G-0668
N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine
GW2974
Chemical & Physical Properties
[ Boiling Point ]:
645.6ºC at 760 mmHg
[ Molecular Formula ]:
C23H21N7
[ Molecular Weight ]:
395.46
[ Flash Point ]:
344.3ºC
[ Exact Mass ]:
395.18600
[ PSA ]:
71.76000
[ LogP ]:
4.30540
[ Vapour Pressure ]:
1.47E-16mmHg at 25°C
[ Index of Refraction ]:
1.71
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
Mol. Biol. Cell 22 , 1121-1134, (2011)
Desmocollin-2 (Dsc2) and desmoglein-2 (Dsg2) are transmembrane cell adhesion proteins of desmosomes. Reduced expression of Dsc2 has been reported in colorectal carcinomas, suggesting that Dsc2 may pla...
Mol. Syst. Biol. 4 , 199, (2008)
Translation of large-scale data into a coherent model that allows one to simulate, predict and control cellular behavior is far from being resolved. Assuming that long-term cellular behavior is reflec...
Br. J. Cancer 100 , 941-9, (2009)
There is a pressing need to identify new drug targets and novel approaches for treatment of non-small-cell lung carcinoma (NSCLC). Members of the epidermal growth factor receptor (EGFR) and Met recept...