p-anisidine hydrochloride

Suppliers

Names

[ CAS No. ]:
20265-97-8

[ Name ]:
p-anisidine hydrochloride

[Synonym ]:
4-Methoxyaniline hydrochloride
4-Anisidine Hydrochloride
p-methoxyaniline hydrochloride
EINECS 243-657-0
4-methoxyphenylaniline hydrochloride
DSSTox_CID_93
p-anisidine HCl
MFCD00036388
p-anisidine hydrochloride
p-methoxyphenylammonium chloride

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
265.9ºC at 760mmHg

[ Melting Point ]:
216-219 °C

[ Molecular Formula ]:
C7H10ClNO

[ Molecular Weight ]:
159.61300

[ Flash Point ]:
114.6ºC

[ Exact Mass ]:
159.04500

[ PSA ]:
35.25000

[ LogP ]:
2.66060

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BZ6600000
CHEMICAL NAME :
p-Anisidine, hydrochloride
CAS REGISTRY NUMBER :
20265-97-8
LAST UPDATED :
199712
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C7-H9-N-O.Cl-H
MOLECULAR WEIGHT :
159.63
WISWESSER LINE NOTATION :
ZR DO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2163 gm/kg/1Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Endocrine - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
116 gm/kg/92W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
1 mg/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7(Suppl 5),1,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,63,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,63,1982 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
33-26/27/28

[ Safety Phrases ]:
S45-S36/37/39-S28A-S1

[ RTECS ]:
BZ6600000

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Preparation


Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • N-methyl-p-anisidine hydrochloride
  • 3-phenyl-p-anisidine hydrochloride
  • 2-Methoxy-p-anisidine hydrochloride
  • 2-Hydroxy-p-anisidine Hydrochloride
  • N-Methyl-p-anisidine hydrochloride ,98
  • N-(cyclohexylmethyl)-4-methoxy-N-(2-piperidin-1-ylethyl)aniline,hydrochloride
  • rac-ethyl (1R,6S,7S,8S)-8-aminobicyclo[4.2.0]octane-7-carboxylate
  • rac-(1R,6S,7S,8S)-8-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)bicyclo[4.2.0]octane-7-carboxylic acid
  • 4-{[(Benzyloxy)carbonyl]amino}-3-iodo-5-nitrobenzoic acid
  • tert-butyl N-(4-hydroxy-2-methylbutyl)-N-[1-(3-methoxy-1,2-thiazol-5-yl)ethyl]carbamate
  • Tert-butyl 7-(hydroxymethyl)-1,2,3,5-tetrahydro-4,1-benzoxazepine-1-carboxylate
  • rac-tert-butyl N-[(1R,2S)-1-hydroxy-2,3-dihydro-1H-inden-2-yl]-N-methylcarbamate
  • tert-butyl N-{4-[(3R)-3-hydroxypyrrolidin-1-yl]phenyl}carbamate
  • tert-butyl N-[4-(3-hydroxypiperidin-1-yl)-2-methylphenyl]carbamate
  • tert-butyl N-ethyl-N-[(1R)-1-[(2R)-oxolan-2-yl]-2-phenylethyl]carbamate
  • tert-butyl N-[3-(4,4-difluoropiperidin-1-yl)-2-hydroxypropyl]carbamate
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