3,3'-Dimethoxybenzidine dihydrochloride
Suppliers
Names
[ CAS No. ]:
20325-40-0
[ Name ]:
3,3'-Dimethoxybenzidine dihydrochloride
[Synonym ]:
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, hydrochloride (1:2)
[1,1'-biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, dihydrochloride
3,3'-Dimethoxybenzidine dihydrochloride
3,3'-Dimethoxy-4,4'-diaminobiphenyl dihydrochloride
3,3'-Dimethoxy-[1,1'-biphenyl]-4,4'-diamine dihydrochloride
MFCD00012488
3,3′-Dimethoxybenzidine dihydrochloride
3,3'-Dimethoxy-4,4'-biphenyldiamine dihydrochloride
DMB DIHYDROCHLORIDE
o-Dianisidinehydrochloride
O-DIANISIDINE REAGENT
BLUE BN BASE DIHYDROCHLORIDE
2-Dianisidine dihydrochloride
EINECS 243-737-5
3,3‘-Dimethoxybenzidine dihydrochloride
2-Dianisidinedihydrochloride
o-Dianisidine Dihydrochloride
3,3'-Dimethoxy-benzidin,Dihydrochlorid
2-Dianisidinedi2HCl
Fast Blue B
3,3'-dimethoxybiphenyl-4,4'-ylenediammonium dichloride
33DIMETHOXYBENZIDINE2HCL
3,3'-dimethoxy-benzidine,dihydrochloride
3,3'-dimethoxybiphenyl-4,4'-diamine dihydrochloride
o-Dianisidine dihydr
o-Dianisidine (dihydrochloride)
Chemical & Physical Properties
[ Boiling Point ]:
391.3ºC at 760 mmHg
[ Melting Point ]:
268 °C
[ Molecular Formula ]:
C14H18Cl2N2O2
[ Molecular Weight ]:
317.211
[ Flash Point ]:
206℃
[ Exact Mass ]:
316.074524
[ PSA ]:
70.50000
[ LogP ]:
5.30160
[ Water Solubility ]:
1-5 g/100 mL at 20 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DD1050000
- CHEMICAL NAME :
- Benzidine, 3,3'-dimethoxy-, dihydrochloride
- CAS REGISTRY NUMBER :
- 20325-40-0
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C14-H16-N2-O2.2Cl-H
- MOLECULAR WEIGHT :
- 317.24
- WISWESSER LINE NOTATION :
- 1OR BZ ER DZ CO1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9100 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8271 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9009 mg/kg/39W-C
- TOXIC EFFECTS :
- Blood - other changes Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1040 mg/kg/1Y-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Reproductive - Tumorigenic effects - testicular tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5760 mg/kg/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1152 mg/kg/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - uterine tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11 gm/kg/51W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6497 mg/kg/91W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-372,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-DIANISIDINE-BASED DYES-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7012 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 489 (estimated) No. of Female Employees: 300 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H350
[ Precautionary Statements ]:
P201-P308 + P313
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R22;R45
[ Safety Phrases ]:
S53-S45
[ RIDADR ]:
2811
[ WGK Germany ]:
3
[ RTECS ]:
DD1050000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2923900090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2923900090
[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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