3,4-Dimethoxyphenol

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Names

[ CAS No. ]:
2033-89-8

[ Name ]:
3,4-Dimethoxyphenol

[Synonym ]:
Phenol,3,4-dimethoxy
3,4 dimethoxyphenol
MFCD00008390
Phenol,4-dimethoxy
3,4-Dimethoxyphenol
4-Hydroxyveratrole
3,4-Dimethoxybenzolol
1-hydroxy-3,4-dimethoxybenzene
EINECS 217-995-4
3,4-dimethoxy phenol
Phenol, 3,4-dimethoxy-
4-Hydroxy-1.2-dimethoxy-benzol

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
271.2±20.0 °C at 760 mmHg

[ Melting Point ]:
79-82 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀O₃

[ Molecular Weight ]:
154.163

[ Flash Point ]:
117.8±21.8 °C

[ Exact Mass ]:
154.062988

[ PSA ]:
38.69000

[ LogP ]:
1.25

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.523

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2909500000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

veratraldehyde
(3,4-dimethoxyphenyl) formate
4-Bromoveratrole
1,2-Dimethoxybenzene
3,4-Dimethoxyphenylmagnesium bromide
3,4-dimethoxy-(1'-hydroxy-1'-methylethyl)benzene
4-(Benzyloxy)-1,2-dimethoxybenzene
2-Hydroxy-4,5-dimethoxybenzoic acid
Acetic acid 3,4-dimethoxyphenyl ester
Ethanol

DownStream

6,7-DIMETHOXY-4-METHYL-CHROMAN-2-ONE
2,4,5-trimethoxybenzoic acid
4-Chromanone
2-hydroxy-4,5-dimethoxybenzaldehyde
1,2-Dimethoxybenzene
2,4,5-Trimethoxybenzaldehyde
4-(chloromethyl)-6,7-dimethoxychromen-2-one
2-Benzofurancarboxylicacid,5,6-dihydroxy-3-methyl-(8CI)
methoxybenzoquinone
2'-hydroxy-4',5'-dimethoxyacetophenone

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Ring-closing metathesis for the synthesis of 2H-and 4H-chromenes. van Otterlo WAL, et al.

Tetrahedron 61(42) , 9996-10006, (2005)

Lowering effect of phenolic glycosides on the rise in postprandial glucose in mice.

Biosci. Biotechnol. Biochem. 61(9) , 1531-5, (1997)

Glycosides were screened for their lowering effect on the postprandial blood glucose rise in vivo. The effect of phlorizin and other phenolic glycosides on the postprandial blood glucose response to g...

5,6-Dimethoxybenzofuran-3-one derivatives: a novel series of dual Acetylcholinesterase/Butyrylcholinesterase inhibitors bearing benzyl pyridinium moiety.

Daru 21(1) , 15, (2013)

Several studies have been focused on design and synthesis of multi-target anti Alzheimer compounds. Utilizing of the dual Acetylcholinesterase/Butyrylcholinesterase inhibitors has gained more interest...

3,4-Dimethoxyphenol
5-bromo-3,4-dimethoxyphenol
6-Allyl-3,4-dimethoxyphenol
2-Allyl-3,4-dimethoxyphenol
2-hydroxy-3,4-dimethoxyphenol
6-(3-chloropropanoyl)-3,4-dimethoxyphenol
Methyl 4-(2-amino-1,1-difluoroethyl)-2-methylbenzoate
1-(Hex-5-yn-2-yl)-4-(trifluoromethyl)benzene
1-[3-(Trifluoromethyl)pyridin-4-yl]cyclohexane-1-carboxylic acid
3-{[6-(Trifluoromethyl)pyridin-3-yl]methyl}azetidin-3-ol
3,4,4,4-Tetrafluorobutanethioamide
3-(2,6-Difluoro-3-nitrophenyl)-1,1,1-trifluoropropan-2-one
3-(4-Methoxypyridin-2-yl)prop-2-en-1-ol
1-(3-Bromo-2-hydroxyphenyl)-2,2,2-trifluoroethan-1-one
1-(2,6-Difluoro-3-nitrophenyl)-2,2-difluoroethan-1-one
2-[2-Fluoro-5-(trifluoromethyl)phenyl]propanal

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