HA-1077 (hydrochloride)
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Names
[ CAS No. ]:
203911-27-7
[ Name ]:
HA-1077 (hydrochloride)
[Synonym ]:
HA-1077 (hydrochloride)
Fasudil dihydrochloride
5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline dihydrochloride hydrate
HA-1077 dihydrochloride
Isoquinoline, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride, hydrate (1:2:1)
HA-1077 dihydrochloride,1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride,Fasudil dihydrochloride
Chemical & Physical Properties
[ Molecular Formula ]:
C14H21Cl2N3O3S
[ Molecular Weight ]:
382.306
[ Exact Mass ]:
381.068054
[ PSA ]:
79.91000
[ LogP ]:
4.10600
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
HM4031166
[ HS Code ]:
2942000000
Customs
[ HS Code ]: 2942000000
Articles
Br. J. Pharmacol. 98 , 1091, (1989)
The in vitro and in vivo vasorelaxant effects of HA1077, 1-(5-isoquinolinesulphonyl)-homopiperazine HCl, a novel vasodilator were examined. The inhibitory effects of HA1077 on contractile responses to...
J. Pharmacol. Exp. Ther. 259 , 738, (1991)
The effects of a newly developed vasodilator agent, HA1077 [1-(5-isoquinolinesulfonyl)-homopiperazine hydrochloride], were investigated on the proliferation of cultured bovine aortic vascular smooth m...
Eur. J. Pharmacol. 195 , 267, (1991)
We examined the effects of HA1077, a potent inhibitor of protein kinases in vitro, on the relationship between tension and myosin-light chain (MLC20) phosphorylation in the initial phase of contractio...