(1R,2R)-(-)-1,2-Diaminocyclohexane

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Names

[ CAS No. ]:
20439-47-8

[ Name ]:
(1R,2R)-(-)-1,2-Diaminocyclohexane

[Synonym ]:
RR-DIAMINOCYCLOHEXANE
(+)-S,S-1,2-Diaminocyclohexane
1,2-Cyclohexanediamine, (1S,2S)-
(1S,2S)-1,2-Cyclohexanediamine
(1R,2R)-(-)-1
(1S,2S)-Cyclohexan-1,2-diamin
(1R)-(-)-trans-1,2-Diaminocyclohexane
trans-1,2-Diaminocyclohexane
(1R,2R)-(-)-1,2-Cyclohexanediamine
2-DiaMinocyclohexane
(1R,2R)-Cyclohexane-1,2-diamine
1R,2R-Diaminocyclohexane
R-DACH
(1S,2S)-Cyclohexane-1,2-diamine
EINECS 211-776-7
trans-1,2-Cyclohexanediamine
MFCD00062985
RR-DAC
(1R,2R)-(-)-1,2-DIAMINO CYCLOHEXANE

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
193.6±0.0 °C at 760 mmHg

[ Melting Point ]:
41-45 °C

[ Molecular Formula ]:
C₆H₁₄N₂

[ Molecular Weight ]:
114.19

[ Flash Point ]:
76 ºC

[ Exact Mass ]:
114.115700

[ PSA ]:
52.04000

[ LogP ]:
-0.12

[ Vapour Pressure ]:
0.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.484

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3259 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2921300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(1R,2R)-2-azido-N-((R)-1-phenylethyl)cyclohexanamine
1,2-Diaminocyclohexane
(R,R)-(-)-1,2-Diaminocyclohexane
(1R,2R)-Cyclohexane-1,2-diamine (2S,3S)-2,3-dihydroxysuccinate
Cyclohexene oxide
7-((R)-1-phenylethyl)-7-azabicyclo[4.1.0]heptane
2-(((R)-1-phenylethyl)amino)cyclohexanol
cis-1,2-Cyclohexanediamine dihydrochloride
Dimethyl malonate
Cyclohexene

DownStream

1-BOC-2-METHYL-4-PIPERIDINONE
N-[(1R,2R)-2-aminocyclohexyl]naphthalene-1-sulfonamide
trans(−)-DDCP
(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine
Oxaliplatin
(1R,2R)-2-AMINO-CYCLOPETANECARBOXYLICACIDHYDROCHLORIDESALT
(1R,2R)-trans-N-Boc-1,2-Cyclohexanediamine
(1R,2R)-Trost ligand
(1R,2R)-1,2-N,N'-bis[(methane-sulfonyl)amino]-cyclohexane
1-(3-triethoxysilylpropyl)-3-[(1R,2R)-2-(3-triethoxysilylpropylcarbamoylamino)cyclohexyl]urea

Customs

[ HS Code ]: 2921300090

[ Summary ]:
2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Steric modifications tune the regioselectivity of the alkane oxidation catalyzed by non-heme iron complexes.

Inorg. Chem. 50(24) , 12651-60, (2011)

Iron complexes with the tetradentate N-donor ligand N,N'-di(phenylmethyl)-N,N'-bis(2-pyridinylmethyl)-1,2-cyclohexanediamine (bbpc) are reported. Despite the benzyl groups present on the amines, the i...

Antitumor platinum(II) complexes of N-monoalkyl-1R, 2R-diaminocyclohexane derivatives with alkyl groups as hindrance.

J. Inorg. Biochem. 112 , 68-76, (2012)

A number of platinum (II) complexes, characteristic of (1R,2R)-N(1)-alkyl-1,2-diaminocyclohexane derivatives as carrier ligands, were designed, synthesized and characterized, where the alkyl group ser...

Synthesis, in vitro cytotoxicity, and interaction with DNA of platinum(II) complexes with N-monocycloalkyl derivatives of 1R,2R-diaminocyclohexane as carrier ligands.

ChemMedChem 7(4) , 642-9, (2012)

A series of platinum(II) complexes with N-monocyclopentyl/cyclohexyl derivatives of 1R,2R-diaminocyclohexane as carrier ligands and dicarboxylate anions as leaving groups were synthesized and characte...

(1R,2R)-(-)-1,2-Diaminocyclohexane
(1R,2R)-(-)-1,2-diaminocyclohexane hydrochloride
(1R,2R)-1,2-Dimethyl-cyclohexane
(1R,2R)-1,2-N,N'-bis[(methane-sulfonyl)amino]-cyclohexane
(1R,2R)-1,2-bis(2-methoxyphenyl)-N1,N2-dimethylethane-1,2-diamine
(1R,2R)-1,2-bis(4-chlorophenyl)-N1,N2-dimethylethane-1,2-diamine