4-[bis(2-chloroethyl)amino]benzamide

Names

[ CAS No. ]:
2045-42-3

[ Name ]:
4-[bis(2-chloroethyl)amino]benzamide

Chemical & Physical Properties

[ Density]:
1.293g/cm3

[ Boiling Point ]:
434.7ºC at 760 mmHg

[ Molecular Formula ]:
C11H14Cl2N2O

[ Molecular Weight ]:
261.14800

[ Flash Point ]:
216.7ºC

[ Exact Mass ]:
260.04800

[ PSA ]:
46.33000

[ LogP ]:
2.76980

[ Vapour Pressure ]:
9.3E-08mmHg at 25°C

[ Index of Refraction ]:
1.593

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV2355000
CHEMICAL NAME :
Benzamide, 4-(bis(2-chloroethyl)amino)-
CAS REGISTRY NUMBER :
2045-42-3
BEILSTEIN REFERENCE NO. :
2810538
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H14-Cl2-N2-O
MOLECULAR WEIGHT :
261.17
WISWESSER LINE NOTATION :
ZVR DN2G2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
313 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,167,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
279 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,167,1965

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-[bis(2-chloroethyl)amino]benzonitrile

DownStream

Related Compounds

  • N-[4-(acridin-9-ylamino)butyl]-4-[bis(2-chloroethyl)amino]benzamide
  • 4-[bis(2-chloroethyl)amino]-N-(2-chloroethyl)benzamide
  • 4-[bis(2-chloroethyl)amino]-N,N-dimethyl-benzamide
  • 4-[bis(2-chloroethyl)amino]-N-[(4-chlorophenyl)methylideneamino]benzamide
  • 4-[bis(2-chloroethyl)amino]-N-[4-(quinolin-4-ylamino)phenyl]benzamide hydrochloride
  • [4-[bis(2-chloroethyl)amino]phenyl]methyl hexadecanoate
  • (3S,4R,5R)-5-(2-Amino-4-oxo-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-7(4H)-yl)-4-hydroxytetrahydrofuran-3-yl hydrogen (2-methyl-1H-imidazol-1-yl)phosphonate
  • 2,5-Dioxopyrrolidin-1-yl 8-phenyloctanoate
  • Benzyl 2,2-difluoro-3-(hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxylate
  • 14-(Aminooxy)-3,6,9,12-tetraoxatetradecanoic acid
  • N-((11bS)-4-(((11bS)-2,6-Bis(3,5-diisopentylphenyl)-4-(((trifluoromethyl)sulfonyl)imino)-4l5-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)imino)-2,6-bis(3,5-diisopentylphenyl)-4l5-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)-1,1,1-trifluoromethanesulfonamide
  • ((2,5-Bis((2-ethylhexyl)oxy)-1,4-phenylene)bis(thiophene-5,2-diyl))bis(trimethylstannane)
  • tert-Butyl (9-amino-6-oxaspiro[3.5]nonan-2-yl)carbamate
  • (E)-2-(4-(1,2-Diphenyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)vinyl)benzylidene)malononitrile
  • tert-Butyl (7S)-7-cyano-1-oxo-2,5-diazaspiro[3.4]octane-5-carboxylate
  • Methyl 6-(4-(2-amino-3-chloropyridin-4-yl)piperidin-1-yl)-2-chloropyrimidine-4-carboxylate
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