4-[bis(2-chloroethyl)amino]benzamide

Names

[ CAS No. ]:
2045-42-3

[ Name ]:
4-[bis(2-chloroethyl)amino]benzamide

Chemical & Physical Properties

[ Density]:
1.293g/cm3

[ Boiling Point ]:
434.7ºC at 760 mmHg

[ Molecular Formula ]:
C11H14Cl2N2O

[ Molecular Weight ]:
261.14800

[ Flash Point ]:
216.7ºC

[ Exact Mass ]:
260.04800

[ PSA ]:
46.33000

[ LogP ]:
2.76980

[ Vapour Pressure ]:
9.3E-08mmHg at 25°C

[ Index of Refraction ]:
1.593

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV2355000
CHEMICAL NAME :
Benzamide, 4-(bis(2-chloroethyl)amino)-
CAS REGISTRY NUMBER :
2045-42-3
BEILSTEIN REFERENCE NO. :
2810538
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H14-Cl2-N2-O
MOLECULAR WEIGHT :
261.17
WISWESSER LINE NOTATION :
ZVR DN2G2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
313 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,167,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
279 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,167,1965

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-[bis(2-chloroethyl)amino]benzonitrile

DownStream

Related Compounds

  • N-[4-(acridin-9-ylamino)butyl]-4-[bis(2-chloroethyl)amino]benzamide
  • 4-[bis(2-chloroethyl)amino]-N-(2-chloroethyl)benzamide
  • 4-[bis(2-chloroethyl)amino]-N,N-dimethyl-benzamide
  • 4-[bis(2-chloroethyl)amino]-N-[(4-chlorophenyl)methylideneamino]benzamide
  • 4-[bis(2-chloroethyl)amino]-N-[4-(quinolin-4-ylamino)phenyl]benzamide hydrochloride
  • [4-[bis(2-chloroethyl)amino]phenyl]methyl hexadecanoate
  • Benzyl 4-[3-[methoxy(methyl)amino]-3-oxopropyl]piperazine-1-carboxylate
  • 3-(1-((5-Ethylthiophen-2-yl)sulfonyl)azetidin-3-yl)imidazolidine-2,4-dione
  • 3-(1-((4-Methoxy-3-methylphenyl)sulfonyl)azetidin-3-yl)imidazolidine-2,4-dione
  • Methyl 3-((3-(2,5-dioxoimidazolidin-1-yl)azetidin-1-yl)sulfonyl)thiophene-2-carboxylate
  • 3-(1-((3-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)sulfonyl)azetidin-3-yl)imidazolidine-2,4-dione
  • (2-Phenylmethoxy-3-trityloxypropyl) methanesulfonate
  • 3-(1-(Quinolin-8-ylsulfonyl)azetidin-3-yl)imidazolidine-2,4-dione
  • 3-[3-(2,5-Dioxoimidazolidin-1-yl)pyrrolidine-1-carbonyl]benzonitrile
  • 3-(1-(3'-Methoxy-[1,1'-biphenyl]-4-carbonyl)pyrrolidin-3-yl)imidazolidine-2,4-dione
  • Tert-butyl 4-(5-amino-6-chloro-1,2,4-triazin-3-yl)-4,7-diazaspiro[2.5]octane-7-carboxylate
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