(3R,4S)-3-Azetidinepropanoic acid,1-(4-fluorophenyl)-2-oxo-4[4(phenylmethoxy)phenyl]-methyl ester

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Names

[ CAS No. ]:
204589-82-2

[ Name ]:
(3R,4S)-3-Azetidinepropanoic acid,1-(4-fluorophenyl)-2-oxo-4[4(phenylmethoxy)phenyl]-methyl ester

[Synonym ]:
trans-3(R)-3-(2-oxo-4(S)-(4-benzyloxyphenyl)-1-(4-fluorophenyl)-azetidinyl)-propanoic acid
(3R,4S)-1-(4-fluorophenyl)-3-[3-(hydroxy)-3-oxopropyl]-4-(4-benzyloxyphenyl)-2-azetidinone
3-[(2S,3R)-2-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-4-oxoazetidin-3-yl]propanoic acid
3-((3R,4S)-1-(4-fluorophenyl)-2-oxo-4-(4-(benzyloxy)phenyl)azetidin-3-yl)propionic acid
3-{(2S,3R)-2-[4-(benzyloxy)phenyl]-1-(4-fluorophenyl)-4-oxoazetidin-3-yl}propionic acid
3-[(2S,3R)-2-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-4-oxo-3-azetidinyl]propanoic acid
3-((2S,3R)-2-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-4-oxoazetidin-3-yl)propanoic acid
3-Azetidinepropanoic acid, 1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-, (3R,4S)-
Ezetimibe Intermediate-I

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
687.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H22FNO4

[ Molecular Weight ]:
419.445

[ Flash Point ]:
369.6±31.5 °C

[ Exact Mass ]:
419.153290

[ PSA ]:
66.84000

[ LogP ]:
4.14

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.614

Precursor & DownStream

Precursor

  • Methyl (3R,4S)-1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoate
  • 3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester

DownStream

  • 4'-O-Benzyloxy Ezetimibe
  • Ezetimibe
  • [4-[(2S,3R)-3-[(3R)-3-acetyloxy-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]phenyl] acetate
  • Ezetimibe Ketone
  • (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one
  • (R)-Ezetimibe

Related Compounds

  • 1-((4-Cyanopyridin-2-yl)sulfonyl)piperazine-2-carboxylic acid hydrochloride
  • 5-Fluoro-2-(piperidin-3-ylthio)pyrimidine hydrochloride
  • 1-((6-chloropyridazin-3-yl)methyl)-N-methylpiperidin-4-amine hydrochloride
  • 3-Methyl-3-(4-methylnaphthalen-1-yl)butanoic acid
  • 3-(2,6-Difluoro-4-methoxyphenyl)-3-methylbutan-1-amine
  • 3-(Benzo[b]thiophen-3-yl)-3-methylbutanoic acid
  • 1-((3-Methoxypyrazin-2-yl)methyl)-1,4-diazepane hydrochloride
  • 4-[4-[[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl]phenoxy]benzonitrile
  • N,Na(2)-[(3,6-Dimethoxy-2-nitrophenyl)methylene]bis[formamide]
  • 4Cmj5PF9AD
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