4,4'-PCB

Suppliers

Names

[ CAS No. ]:
2050-68-2

[ Name ]:
4,4'-PCB

[Synonym ]:
Biphenyl,4,4'-dichloro
p,p'-dichlorobiphenyl
4,4'-Dichloro-1,1'-biphenyl
Biphenyl, 4,4'-dichloro-
1,1'-Biphenyl, 4,4'-dichloro-
PCB 15
p,p-Dcbp
4,4'-PCB
MFCD00013641
4,4'-Dichlorobiphenyl
PCB No 15
1,1'-Biphenyl,4,4'-dichloro
EINECS 218-095-4
4,4'-Dichloro-biphenyl
1-chloro-4-(4-chlorophenyl)benzene
4.4'-Dichlorobiphenyl

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
318.0±17.0 °C at 760 mmHg

[ Melting Point ]:
288℃

[ Molecular Formula ]:
C₁₂H₈Cl₂

[ Molecular Weight ]:
223.098

[ Flash Point ]:
145.2±14.5 °C

[ Exact Mass ]:
222.000305

[ LogP ]:
5.12

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.594

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV3912500

CHEMICAL NAME :: 1,1'-Biphenyl, 4,4'-dichloro-

CAS REGISTRY NUMBER :: 2050-68-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H8-Cl2

MOLECULAR WEIGHT :: 223.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg/3D-I

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other hydrolases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 mg/kg/7D-I

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), zonal

MUTATION DATA

TEST SYSTEM :: Insect - Drosophila melanogaster

DOSE/DURATION :: 1 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 342,61,1995

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H304-H315-H336-H373-H410

[ Precautionary Statements ]:
P210-P261-P273-P301 + P310-P331-P501

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
16-26-33-36

[ RIDADR ]:
UN 2315

[ RTECS ]:
DV3912500

[ Packaging Group ]:
II

[ Hazard Class ]:
9

[ HS Code ]:
2903999010

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2903999010

[ Summary ]:
2903999010 2,3,3',4,5,6-hexachloro-1,1'-biphenyl。supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%

Articles

Microbial dehalogenation of 4,4'-dichlorobiphenyl under anaerobic conditions.

Sci. Total Environ. 101(3) , 263-8, (1991)

Anaerobic cultures containing 4,4'-dichlorobiphenyl (4,4'CB) were inoculated with various environmental samples. The degradation of the substrate was followed by gas chromatographic analysis. Three of...

Possible molecular targets of halogenated aromatic hydrocarbons in neuronal cells.

Biochem. Biophys. Res. Commun. 280(5) , 1372-7, (2001)

Halogenated aromatic hydrocarbon including polychlorinated biphenyls (PCBs) are persistent and bioaccumulative environmental toxicants. Although health effects associated with exposure to these chemic...

The effect of chlorine substitution on the disposition of polychlorinated biphenyls following dermal administration.

Toxicol. Appl. Pharmacol. 216(1) , 157-67, (2006)

The fate of selected polychlorobiphenyls (PCBs) was investigated following single dermal administration (0.4 mg/kg) to determine the effects of chlorine content and position on the disposition of PCBs...