1-(4,5-diphenyl-1,3-oxazol-2-yl)-4-methyl-piperazine

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Names

[ CAS No. ]:
20503-88-2

[ Name ]:
1-(4,5-diphenyl-1,3-oxazol-2-yl)-4-methyl-piperazine

Chemical & Physical Properties

[ Density]:
1.143g/cm3

[ Boiling Point ]:
451.8ºC at 760mmHg

[ Molecular Formula ]:
C20H21N3O

[ Molecular Weight ]:
319.40000

[ Flash Point ]:
227ºC

[ Exact Mass ]:
319.16800

[ PSA ]:
32.51000

[ LogP ]:
3.76330

[ Vapour Pressure ]:
2.36E-08mmHg at 25°C

[ Index of Refraction ]:
1.59

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RP6890000
CHEMICAL NAME :
Oxazole, 4,5-diphenyl-2-(4-methyl-1-piperazinyl)-
CAS REGISTRY NUMBER :
20503-88-2
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H21-N3-O
MOLECULAR WEIGHT :
319.44
WISWESSER LINE NOTATION :
T6N DNTJ A1 D- BT5N COJ DR& ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
850 mg/kg
TOXIC EFFECTS :
Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,1092,1968

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 2-Azido-2-[2-(dimethylamino)-1,3-thiazol-5-yl]ethan-1-ol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • (2R)-4-[(tert-butyldimethylsilyl)oxy]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine