5-Iodo-2-pyridinamine

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Names

[ CAS No. ]:
20511-12-0

[ Name ]:
5-Iodo-2-pyridinamine

[Synonym ]:
5-Iodo-pyridin-2-ylamine
2-Amino-5-iodo pyridine
5-iod-2-pyridinamin
2-amino-5-iodopyridine
6-amino-3-iodopyridine
2-Pyridinamine, 5-iodo-
5-Iodo-2-aminopyridine
5-Iodopyridin-2-amine
5-Iodo-2-pyridinamine
2-Pyridinamine,5-iodo
Pyridine,2-amino-5-iodo
MFCD00160312

Chemical & Physical Properties

[ Density]:
2.1±0.1 g/cm3

[ Boiling Point ]:
293.8±25.0 °C at 760 mmHg

[ Melting Point ]:
128-131 °C(lit.)

[ Molecular Formula ]:
C₅H₅IN₂

[ Molecular Weight ]:
220.011

[ Flash Point ]:
131.5±23.2 °C

[ Exact Mass ]:
219.949738

[ PSA ]:
38.91000

[ LogP ]:
2.06

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.703

[ Storage condition ]:
2~8℃

[ Water Solubility ]:
Insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

2-Amino-5-phenylpyridine
2-Fluoro-5-pyridylboronic acid
N-(5-Iodo-pyridin-2-yl)-2,2-dimethyl-propionamide
tert-Butyl (5-iodopyridin-2-yl)carbamate
2-Chloropyridine-5-boronic acid Pinacol ester
2-Fluoropyridine-5-boronic acid pinacol ester
6-IODOIMIDAZO[1,2-A]PYRIDINE
2-Chloro-5-pyridineboronic acid
2-Amino-5-cyanopyridine
2-Fluoro-5-iodopyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Methyl 6-(phenylsulfinyl)imidazo[1,2-a]pyridine-2-carbamate, a potent, new anthelmintic.

J. Med. Chem. 21(2) , 235-7, (1978)

A series of methyl imidazo-[11,2-a]pyridine-2-carbamates was synthesized for anthelmintic testing. The preparation of this class of compounds was simplified by utilization of a novel one-step condensa...

Vibrational spectra and assignments of 2-amino-5-iodopyridine by ab initio Hartree-Fock and density functional methods.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 67(3-4) , 830-6, (2007)

The Fourier transform Raman and Fourier transform infrared spectra of 2-amino-5-iodopyridine were recorded in the solid phase. The equilibrium geometry, harmonic vibrational frequencies, infrared inte...

Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain.

J. Med. Chem. 46(2) , 237-43, (2003)

A series of novel beta-amyloid (A beta) aggregate-specific ligands, 2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyridine, 16(IMPY), and its related derivatives were prepared. An in vitro binding st...