alpha-Chaconine

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Names

[ CAS No. ]:
20562-03-2

[ Name ]:
alpha-Chaconine

[Synonym ]:
chaconine
chaconine,a
a-chaconine with tlc
a-chaconine
a-chaconine from potato sprouts
alpa-chaconine

Chemical & Physical Properties

[ Density]:
1.37 g/cm3

[ Melting Point ]:
228-236ºC

[ Molecular Formula ]:
C45H73NO14

[ Molecular Weight ]:
852.05900

[ Exact Mass ]:
851.50300

[ PSA ]:
220.46000

[ LogP ]:
1.12070

[ Index of Refraction ]:
1.621

[ Water Solubility ]:
pyridine: 10 mg/mL, clear, very faintly yellow

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FL6700000
CHEMICAL NAME :
alpha-Chaconine
CAS REGISTRY NUMBER :
20562-03-2
BEILSTEIN REFERENCE NO. :
0077396
LAST UPDATED :
199612
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C45-H73-N-O14
MOLECULAR WEIGHT :
852.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
84 mg/kg
TOXIC EFFECTS :
Blood - hemorrhage
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
160 mg/kg/8D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
80 mg/kg/2D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
40 mg/kg
SEX/DURATION :
female 5-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
20 mg/kg
SEX/DURATION :
female 5-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
165 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
90 mg/kg/3D (Continuous)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 33,191,1995 *** REVIEWS *** TOXICOLOGY REVIEW FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,61,1979

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R63

[ Safety Phrases ]:
22-36/37

[ RIDADR ]:
UN 1544

[ WGK Germany ]:
3

[ RTECS ]:
FL6700000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)


Related Compounds

  • ALPHA-CHACONINE:ALPHA-SOLANINEMIXTURE
  • alpha-butyl-alpha-phenyl-1H-imidazole-1-propiononitrile
  • ALPHA-D(+)MALTOSE 1-PHOSPHATE DIPOTASSIUM SALT
  • alpha-D-Xylofuranoside,methyl5-thio-,5-acetate(9CI)
  • alpha-docosyl-omega-hydroxy-poly(oxy-2-ethanediyl)
  • (-)-alpha-Cedrene
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-bromo-3-(2,2,2-trifluoroacetamido)-1H-pyrrole-2-carboxylic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • tert-butyl N-[(2R)-2,3-dihydroxypropyl]-N-ethylcarbamate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine