C-6-G HYDRATE-TRIFLUOROACETATE

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Names

[ CAS No. ]:
20736-11-2

[ Name ]:
C-6-G HYDRATE-TRIFLUOROACETATE

[Synonym ]:
Codeine-6-glucuronide

Chemical & Physical Properties

[ Density]:
1.56g/cm3

[ Boiling Point ]:
713.4ºC at 760 mmHg

[ Melting Point ]:
248-250ºC (dec.)

[ Molecular Formula ]:
C₂₄H₂₉NO₉

[ Molecular Weight ]:
475.48800

[ Flash Point ]:
385.2ºC

[ Exact Mass ]:
475.18400

[ PSA ]:
138.15000

[ Vapour Pressure ]:
2.34E-21mmHg at 25°C

[ Index of Refraction ]:
1.692

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H302 + H312 + H332-H370

[ Precautionary Statements ]:
P260-P280-P307 + P311

[ RIDADR ]:
UN 1993C 3 / PGIII

Articles

Lack of effect of paracetamol on the pharmacokinetics and metabolism of codeine in man.

Eur. J. Clin. Pharmacol. 41(4) , 379-82, (1991)

Plasma and urine concentrations of codeine and its measurable metabolites were determined by HPLC in six healthy subjects after a single 30 mg oral dose of codeine either alone or after 7 doses of 1 g...

Species differences in metabolism of codeine: urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits.

Xenobiotica 20(7) , 683-8, (1990)

1. Metabolites of codeine were determined by use of h.p.l.c. in urine of male mice, rats, guinea pigs and rabbits injected with 10 mg codeine/kg subcutaneously. 2. In 24 h urines of these species, unc...

Direct determination of codeine, norcodeine, morphine and normorphine with their corresponding O-glucuronide conjugates by high-performance liquid chromatography with electrochemical detection.

J. Chromatogr. A. 570(2) , 309-20, (1991)

A high-performance liquid chromatographic method has been developed for the detection, separation and measurement of codeine and its metabolites norcodeine, morphine and normorphine, with their glucur...

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