Phenylalanine,N-acetyl-, 2-naphthalenyl ester

Names

[ CAS No. ]:
20874-31-1

[ Name ]:
Phenylalanine,N-acetyl-, 2-naphthalenyl ester

[Synonym ]:
beta-naphthyl N-acetylphenylalaninate
APNE
N-Acetyl-DL-phenylalanin-[2]naphthylester
N-acetyl-DL-phenylalanine-[2]naphthyl ester
naphthalen-2-yl 2-acetamido-3-phenylpropanoate
mv1

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
589.8ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₁₉NO₃

[ Molecular Weight ]:
333.38000

[ Flash Point ]:
310.5ºC

[ Exact Mass ]:
333.13600

[ PSA ]:
55.40000

[ LogP ]:
3.88350

[ Vapour Pressure ]:
6.93E-14mmHg at 25°C

[ Index of Refraction ]:
1.618

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Oxalyl chloride
N-Acetyl-DL-phenylalanine

DownStream

Articles

A simple method to determine trypsin and chymotrypsin inhibitory activity.

J. Biochem. Biophys. Methods 59 , 241-251, (2004)

A colorimetric method for serine protease inhibition was modified using N-Acetyl-DL-Phenylalanine beta-Naphthylester (APNE) as the substrate and o-Dianisidine tetrazotized (oD) as the dye. The reactio...

An association between Schistosoma mansoni worms and an enzymatically-active protease/peptidase in mouse blood.

Parasitology 135 , 467-472, (2008)

An enzyme found previously in extracts of adult Schistosoma mansoni worms, that hydrolysed the chromogenic substrate N-acetyl-DL-phenylalanine beta-naphthyl-ester, has here been further investigated a...

Involvement of proteases in the action of IFN-gamma on WISH cells.

J. Interferon Cytokine Res. 22(8) , 847-52, (2002)

This study investigates the possible involvement of serine proteases in interferon-gamma (IFN-gamma) activity on WISH cells. It was observed that inhibition of (3)H-thymidine incorporation induced by ...

Phenylalanine, N-acetyl-2-nitro-
(R)-2-ACETYLAMINO-3-(2,5-DIFLUORO-PHENYL)-PROPIONIC ACID METHYL ESTER
N-acetyl-2-fluoro-D-phenylalanine
(2S)-2-acetamido-3-(2-bromophenyl)propanoic acid
(2S)-2-acetamido-3-(2-chlorophenyl)propanoic acid
(2S)-2-acetamido-3-(2,4-difluorophenyl)propanoic acid
2-{5-[5-(Trifluoromethyl)pyridin-2-yl]-octahydropyrrolo[3,4-c]pyrrol-2-yl}pyridine-3-carbonitrile
2-{5-[(5-Cyclopropyl-1,3,4-oxadiazol-2-yl)methyl]-octahydropyrrolo[3,4-c]pyrrol-2-yl}-5-(trifluoromethyl)pyridine
2-(2-Oxo-2-{4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl}ethyl)-2,3-dihydropyridazin-3-one
2-[4-(6-Cyclobutylpyrimidin-4-yl)piperazin-1-yl]-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile
3-(3,5-Dimethyl-1,2-oxazol-4-yl)-1-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]propan-1-one
3-{2-[4-(5-fluoro-6-methylpyrimidin-4-yl)piperazin-1-yl]-2-oxoethyl}-6-methyl-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
2-[1-(2,3-dihydro-1H-isoindol-2-yl)-1-oxopropan-2-yl]-6-(trifluoromethyl)-2,3-dihydropyridazin-3-one
2-(5-{5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}-octahydropyrrolo[3,4-c]pyrrol-2-yl)-5-(trifluoromethyl)pyridine
3-[4-(4-Bromothiophene-2-carbonyl)piperazin-1-yl]-6-(trifluoromethyl)pyridazine
2-(Pyridazin-3-yloxy)-1-{4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl}ethan-1-one

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