Phenylalanine,N-acetyl-, 2-naphthalenyl ester

Names

[ CAS No. ]:
20874-31-1

[ Name ]:
Phenylalanine,N-acetyl-, 2-naphthalenyl ester

[Synonym ]:
beta-naphthyl N-acetylphenylalaninate
APNE
N-Acetyl-DL-phenylalanin-[2]naphthylester
N-acetyl-DL-phenylalanine-[2]naphthyl ester
naphthalen-2-yl 2-acetamido-3-phenylpropanoate
mv1

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
589.8ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₁₉NO₃

[ Molecular Weight ]:
333.38000

[ Flash Point ]:
310.5ºC

[ Exact Mass ]:
333.13600

[ PSA ]:
55.40000

[ LogP ]:
3.88350

[ Vapour Pressure ]:
6.93E-14mmHg at 25°C

[ Index of Refraction ]:
1.618

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Oxalyl chloride
N-Acetyl-DL-phenylalanine

DownStream

Articles

A simple method to determine trypsin and chymotrypsin inhibitory activity.

J. Biochem. Biophys. Methods 59 , 241-251, (2004)

A colorimetric method for serine protease inhibition was modified using N-Acetyl-DL-Phenylalanine beta-Naphthylester (APNE) as the substrate and o-Dianisidine tetrazotized (oD) as the dye. The reactio...

An association between Schistosoma mansoni worms and an enzymatically-active protease/peptidase in mouse blood.

Parasitology 135 , 467-472, (2008)

An enzyme found previously in extracts of adult Schistosoma mansoni worms, that hydrolysed the chromogenic substrate N-acetyl-DL-phenylalanine beta-naphthyl-ester, has here been further investigated a...

Involvement of proteases in the action of IFN-gamma on WISH cells.

J. Interferon Cytokine Res. 22(8) , 847-52, (2002)

This study investigates the possible involvement of serine proteases in interferon-gamma (IFN-gamma) activity on WISH cells. It was observed that inhibition of (3)H-thymidine incorporation induced by ...

Phenylalanine, N-acetyl-2-nitro-
(R)-2-ACETYLAMINO-3-(2,5-DIFLUORO-PHENYL)-PROPIONIC ACID METHYL ESTER
N-acetyl-2-fluoro-D-phenylalanine
(2S)-2-acetamido-3-(2-bromophenyl)propanoic acid
(2S)-2-acetamido-3-(2-chlorophenyl)propanoic acid
(2S)-2-acetamido-3-(2,4-difluorophenyl)propanoic acid
2-Cyclopentyl-2-fluoropropane-1,3-diol
3-(Dimethylcarbamoyl)-2-fluoropropanoic acid
3-fluoro-4-hydroxy-N,N-dimethylbutanamide
4-bromo-3-fluoro-N,N-dimethylbutanamide
2-[(Dimethylcarbamoyl)methyl]-2-fluoropropanedioic acid
3-fluoro-4-hydroxy-3-(hydroxymethyl)-N,N-dimethylbutanamide
2-(3-Fluoroazetidin-3-yl)acetonitrile
2-Fluoro-4-oxo-4-(pyrrolidin-1-yl)butanoic acid
3-Fluoro-4-hydroxy-1-(pyrrolidin-1-yl)butan-1-one
4-Bromo-3-fluoro-1-(pyrrolidin-1-yl)butan-1-one

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