chloro(2-hydroxyethyl)mercury

Names

[ CAS No. ]:
2090-53-1

[ Name ]:
chloro(2-hydroxyethyl)mercury

[Synonym ]:
2-chloromercurioethanol
Hydroxyethylmercuric chloride
Clerit 6
Aethanolquecksilberchlorid
Ethanolmercury chloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₂H₅ClHgO

[ Molecular Weight ]:
281.10400

[ Exact Mass ]:
281.97400

[ PSA ]:
20.23000

[ LogP ]:
0.63330

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OW0212500

CHEMICAL NAME :: Mercury, chloro(2-hydroxyethyl)-

CAS REGISTRY NUMBER :: 2090-53-1

LAST UPDATED :: 199606

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C2-H5-Cl-Hg-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 11(7),44,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16500 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 11(7),44,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 48 mg/kg/6W-I

TOXIC EFFECTS :: Liver - liver function tests impaired Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Metabolism (Intermediary) - other proteins

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 11(7),44,1977

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

ethene
mercuric acetate
Aluminium isopropoxide
chloro(2-oxoethyl)mercury

DownStream

Related Compounds

chloro(2-hydroxyethyl)mercury,1-hexadecylpyridin-1-ium,bromide
acetyloxy(2-hydroxyethyl)mercury
bromo(2-hydroxyethyl)mercury
(2-chloro-2-hydroxyethyl)-trimethylazanium
2-[chloro(2-hydroxyethyl)amino]ethanol
2-hydroxyethyl 2-chloropyridine-4-carboxylate
2-(5-chlorothiophen-2-yl)-N-(4-methoxynaphthalen-1-yl)acetamide
2-(5-chlorothiophen-2-yl)-N-(1,2-dihydroacenaphthylen-5-yl)acetamide
2-(5-chlorothiophen-2-yl)-N-(2-phenoxyphenyl)acetamide
(E)-2-(5-chlorothiophen-2-yl)-N-(4-(phenyldiazenyl)phenyl)acetamide
2-(5-Chlorothiophen-2-yl)-1-(4-phenylpiperazin-1-yl)ethanone
2-(5-chlorothiophen-2-yl)-N-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]acetamide
2-(2-(5-Chlorothiophen-2-yl)acetamido)thiophene-3-carboxamide
2-(2-(5-chlorothiophen-2-yl)acetamido)-N-methylthiophene-3-carboxamide
2-(5-chlorothiophen-2-yl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)acetamide
N-(1-cyanocyclopentyl)-2-[cyclopropyl({1-[3-(trifluoromethyl)phenyl]ethyl})amino]acetamide

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