D-Valine,3,3'-dithiobis-

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Names

[ CAS No. ]:
20902-45-8

[ Name ]:
D-Valine,3,3'-dithiobis-

[Synonym ]:
MFCD00004264
penicillinamine disulfide
D-PENICILLAMINE DISULPHIDE
Penicillamine disulfide
d-3,3-dimethyl cysteine disulphide
penicillamine disulphide
EINECS 244-107-2
3,3''-Dithiobis-D-valine
3,3'-dithiodi-D-valine
D-PENICILLAMINE DISULFIDE

Chemical & Physical Properties

[ Density]:
1.353g/cm3

[ Boiling Point ]:
467ºC at 760mmHg

[ Melting Point ]:
204ºC (dec.)(lit.)

[ Molecular Formula ]:
C10H20N2O4S2

[ Molecular Weight ]:
296.40700

[ Flash Point ]:
236.2ºC

[ Exact Mass ]:
296.08600

[ PSA ]:
177.24000

[ LogP ]:
2.14940

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.595

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • D-penicillamine disulfide dimethyl ester
  • D-penicillamine
  • Ethanesulfinothioicacid, S-ethyl ester
  • Ammonia
  • Ferric chloride

DownStream

  • (S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid

Articles

Quantification of pipecolic acid in plasma, and of urinary cystine in the presence of penicillamine-cystine disulfide, with the Beckman 6300 amino acid analyzer.

Clin. Chem. 33(7) , 1302-3, (1987)

Determination of penicillamine, penicillamine disulfide and penicillamine-glutathione mixed disulfide by high-performance liquid chromatography with electrochemical detection.

J. Chromatogr. A. 491(2) , 341-54, (1989)

Methodology is described for the simultaneous determination of D-penicillamine, penicillamine disulfide and the penicillamine-glutathione mixed disulfide, as well as glutathione and glutathione disulf...

Methods for assaying D-penicillamine in a clinical setting.

Clin. Invest. Med. 7(1) , 31-4, (1984)

Penicillamine disulfides have been analysed by automatic amino acid analysis. Because the free thiol reacts poorly with ninhydrin, other detection methods are preferred, particularly high pressure liq...


More Articles


Related Compounds

  • D-Valine,3,3'-dithiobis-,copper complex
  • (2S)-2-amino-3-[(1S)-1-amino-1-carboxy-2-methylpropan-2-yl]sulfanylselanylsulfanyl-3-methylbutanoic acid
  • (2R)-2-acetamido-3-[[(1R)-1-acetamido-1-carboxy-2-methylpropan-2-yl]disulfanyl]-3-methylbutanoic acid
  • D-Valine, 3-hydroxy-2-methyl-, methyl ester (9CI)
  • D-tert-Leucine Methyl Ester Hydrochloride
  • D-VALINE, 3-METHYL-N-[(PHENYLMETHOXY)CARBONYL]-, METHYL ESTER