2-Hydroxyethylflurazepam

Names

[ CAS No. ]:
20971-53-3

[ Name ]:
2-Hydroxyethylflurazepam

[Synonym ]:
7-Chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-1,3-dihydro-2H-1,4 -benzodiazepin-2-one

Chemical & Physical Properties

[ Density]:
1.36g/cm3

[ Boiling Point ]:
567.1ºC at 760 mmHg

[ Molecular Formula ]:
C17H14ClFN2O2

[ Molecular Weight ]:
332.75700

[ Flash Point ]:
296.8ºC

[ Exact Mass ]:
332.07300

[ PSA ]:
52.90000

[ LogP ]:
2.15600

[ Vapour Pressure ]:
1.07E-13mmHg at 25°C

[ Index of Refraction ]:
1.629

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DF2370110
CHEMICAL NAME :
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxye thyl)-
CAS REGISTRY NUMBER :
20971-53-3
LAST UPDATED :
199609
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H14-Cl-F-N2-O2
MOLECULAR WEIGHT :
332.78
WISWESSER LINE NOTATION :
T67 GNV JN IHJ CG G2Q KR BF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
940 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
26RAAN "Benzodinzenines," Garattini, S., et al., New York, Raven Press, 1973 Volume(issue)/page/year: -,46,1973

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Flurazepam dihydrochloride

DownStream

Related Compounds

  • 2-HYDROXYETHYLFLURAZEPAM-D4
  • 2-[(4-aminobenzoyl)-benzylamino]ethyl-diethylazanium,chloride
  • 2-methyl-2-methylsulfanylpropanenitrile
  • 2-(4-methoxyphenyl)-4-nitrobenzoic acid
  • 2-(4-methoxyphenyl)-5-methylbenzoic acid
  • 2-(4-methoxyphenyl)-6-methylbenzoic acid
  • 1-(2-Methylphenyl)homopiperazine hydrochloride
  • 2-[(2,3-Dihydro-1H-inden-1-yl)amino]-N-methylacetamide
  • o-(Benzofuran-2-ylmethyl)hydroxylamine
  • 2-[(1-Cyclopropyl-1H-tetrazol-5-yl)thio]-1-phenyl-1-butanone
  • 2-(Dimethylamino)-2-(4-(trifluoromethoxy)phenyl)acetonitrile
  • 2-(3,4-Dichlorophenyl)-2-(diethylamino)acetonitrile
  • 2-(2-Bromophenyl)-2-(morpholin-4-yl)acetonitrile
  • 8-Morpholin-4-yl-1,4-dioxaspiro[4.5]decane-8-carbonitrile
  • 2-(5-Bromo-2-fluorophenyl)-2-(morpholin-4-yl)acetonitrile
  • 2-(Dimethylamino)-2-(1-methyl-1H-pyrazol-4-yl)acetic acid
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