YO-01027

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Names

[ CAS No. ]:
209984-56-5

[ Name ]:
YO-01027

[Synonym ]:
N-[(3,5-Difluorophenyl)acetyl]-N-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide
Deshydroxy LY-411575
Benzeneacetamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-
N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
DBZ
Dibenzazepine
YO-01027

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
801.3±65.0 °C at 760 mmHg

[ Melting Point ]:
257-259ºC

[ Molecular Formula ]:
C₂₆H₂₃F₂N₃O₃

[ Molecular Weight ]:
463.476

[ Flash Point ]:
438.4±34.3 °C

[ Exact Mass ]:
463.170746

[ PSA ]:
78.51000

[ LogP ]:
4.60

[ Appearance of Characters ]:
white to beige

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.637

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
DMSO: soluble15mg/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29337900

Articles

Notch inhibition allows oncogene-independent generation of iPS cells.

Nat. Chem. Biol. , doi:10.1038/nchembio.1552, (2014)

The reprogramming of somatic cells to pluripotency using defined transcription factors holds great promise for biomedicine. However, human reprogramming remains inefficient and relies either on the us...

The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids.

Nat. Commun. 6 , 8989, (2015)

The epithelial lining of the fallopian tube is of critical importance for human reproduction and has been implicated as a site of origin of high-grade serous ovarian cancer. Here we report on the esta...