Sitaxentan sodium
Suppliers
Names
[ CAS No. ]:
210421-74-2
[ Name ]:
Sitaxentan sodium
[Synonym ]:
Thelin
Sodium (4-chloro-3-methyl-1,2-oxazol-5-yl)({2-[(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thienyl}sulfonyl)azanide
3-Thiophenesulfonamide, N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-, sodium salt (1:1)
Sitax
Sitaxsentan sodium
Sitaxentan sodium [USAN]
Sitaxentan sodium
Sitaxsentan (sodium)
Chemical & Physical Properties
[ Molecular Formula ]:
C18H14ClN2NaO6S2
[ Molecular Weight ]:
476.88600
[ Exact Mass ]:
475.98800
[ PSA ]:
135.56000
[ LogP ]:
4.90080
[ Appearance of Characters ]:
white to beige
[ Storage condition ]:
room temp
[ Water Solubility ]:
H2O: soluble10mg/mL (clear solution)
Safety Information
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
XN0296600
Articles
Oncogenesis 4 , e146, (2015)
RUNX1/ETO (RE), the t(8;21)-derived leukemic transcription factor associated with acute myeloid leukemia (AML) development, deregulates genes involved in differentiation, self-renewal and proliferatio...
Biomed Res. Int. 2015 , 386165, (2015)
B-cell acute lymphoblastic leukemia (B-ALL) is a serious public health problem in the pediatric population worldwide, contributing to 85% of deaths from childhood cancers. Understanding the biology of...
Oncogenesis 3 , e122, (2014)
Chronic myelogenous leukemia (CML) is maintained by a minor population of leukemic stem cells (LSCs) that exhibit innate resistance to tyrosine kinase inhibitors (TKIs) targeting BCR-ABL. Innate resis...